Evidence map›Paper›PMID 29848980›Full record

ArticleInternational journal of environmental research and public health2018

Clinical Relevant Polymorphisms Affecting Clopidogrel Pharmacokinetics and Pharmacodynamics: Insights from the Puerto Rico Newborn Screening Program.

Dagmar F Hernandez-Suarez, Jonnalie C Tomassini-Fernandini, Angelica Cuevas, Anyelis N Rosario-Berrios, Héctor J Nuñez-Medina, Dariana Padilla-Arroyo, Nannette Rivera, Jennifer Liriano, Rocio K Vega-Roman, Jessicca Y Renta and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Dagmar F Hernandez-SuarezDivision of Cardiovascular Medicine, School of Medicine, University of Puerto Rico Medicine Sciences Campus, P.O. Box 365067, San Juan, PR 00936-5067, USA. dagmar.hernandez@upr.edu.ORCID 0000-0003-1850-9078
Jonnalie C Tomassini-FernandiniDepartment of Biology, Natural Sciences, University of Puerto Rico Rio Piedras Campus, San Juan, PR 00931, USA. jonnalie.tomassini@upr.edu.
Angelica CuevasDepartment of Biology, Natural Sciences, University of Puerto Rico Rio Piedras Campus, San Juan, PR 00931, USA. angelica.cuevas30@yahoo.com.
Anyelis N Rosario-BerriosDepartment of Biology, Natural Sciences, University of Puerto Rico Rio Piedras Campus, San Juan, PR 00931, USA. anyelis.rosario@upr.edu.
Héctor J Nuñez-MedinaDivision of Cardiovascular Medicine, School of Medicine, University of Puerto Rico Medicine Sciences Campus, P.O. Box 365067, San Juan, PR 00936-5067, USA. hector.nunez@upr.edu.
Dariana Padilla-ArroyoPharmaceutical Sciences Department, University of Puerto Rico Medical Sciences Campus, San Juan, PR 00936, USA. dariana.padilla@upr.edu.
Nannette RiveraDepartment of Biology, Natural Sciences, University of Puerto Rico Rio Piedras Campus, San Juan, PR 00931, USA. nannette.rivera1@upr.edu.
Jennifer LirianoDepartment of Biology, Natural Sciences, University of Puerto Rico Rio Piedras Campus, San Juan, PR 00931, USA. jenniferliriano14@gmail.com.
Rocio K Vega-RomanDepartment of Biology, Natural Sciences, University of Puerto Rico Bayamon Campus, Bayamon, PR 00959, USA. rocio.vega@upr.edu.
Jessicca Y RentaDepartment of Biochemistry, University of Puerto Rico Medical Sciences Campus, San Juan, PR 00936, USA. jessicca.renta@upr.edu.
Kyle MelinDepartment of Pharmacy Practice, University of Puerto Rico Medical Sciences Campus, San Juan, PR 00936, USA. kyle.melin@upr.edu.ORCID 0000-0002-4698-8021
Jorge DucongePharmaceutical Sciences Department, University of Puerto Rico Medical Sciences Campus, San Juan, PR 00936, USA. jorge.duconge@upr.edu.
University of Puerto Rico, Medical Sciences Campus · PRUniversity of Puerto Rico at Río Piedras · PRUniversity of Puerto Rico at Bayamón · PR

Funding

Upstream Regulation and Downstream effectors of c-MYC in Ovarian CancerU54MD007600 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Carmen M Velez Vega · 2017 to 2026
$35.8M
MSHS Translational Science HubUL1TR001433 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2015 to 2019
$26.6M
TRANSLATIONAL PROTEOMICS CENTERG12MD007600 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI FERNANDEZ-REPOLLET, EMMA · 2012 to 2016
$11.0M
Hispanic Clinical and Translational Research Education and Career Development ProgramR25MD007607 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Karen G. Martinez Gonzalez, Barbara Segarra-Vazquez · 2012 to 2026
$7.4M
Conduits: MSHS Translational Science HubTL1TR001434 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GABRILOVE, JANICE L · 2015 to 2019
$2.1M
NCATS NIH HHS TL1 TR001434NCATS NIH HHS UL1 TR001433NIMHD NIH HHS G12 MD007600NIMHD NIH HHS R25 MD007607NIMHD NIH HHS U54 MD007600
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotideAryldialkylphosphataseATP Binding Cassette Transporter, Subfamily BClopidogrelCross-Sectional StudiesCytochrome P-450 CYP2C19FemaleGene FrequencyGenetic MarkersGenotypeHumansInfant, NewbornMaleNeonatal ScreeningPharmacogeneticsPlatelet Aggregation InhibitorsABCB1 protein, humanAryldialkylphosphataseATP Binding Cassette Transporter, Subfamily BClopidogrelCYP2C19 protein, humanCytochrome P-450 CYP2C19Genetic MarkersP2RY12 protein, humanPlatelet Aggregation InhibitorsPON1 protein, humanReceptors, Purinergic P2Y12allele frequencyclopidogrelgenotypespharmacogeneticsPuerto Ricans

Identifiers

PMID29848980
PMCPMC6025039
OpenAlexW2795595769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.