Evidence map›Paper›PMID 29848976›Full record

ArticleScientia pharmaceutica2018

Synthesis, Crystal Structure, and Biological Activity of Ethyl 4-Methyl-2,2-dioxo-1

Igor V Ukrainets, Anna A Burian, Vyacheslav N Baumer, Svitlana V Shishkina, Lyudmila V Sidorenko, Igor A Tugaibei, Natali I Voloshchuk, Pavlo S Bondarenko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientia pharmaceutica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Anti-cancer agents in medicinal chemistry · 2025
    Article
  3. Article
  4. Methyl 5-chloro-4-hy-droxy-2,2-dioxo-1Acta crystallographica. Section E, Crystallographic communications · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Igor V UkrainetsDepartment of Pharmaceutical Chemistry, National University of Pharmacy, 53 Pushkinska st., 61002 Kharkiv, Ukraine. igor.v.ukrainets@gmail.com.ORCID 0000-0002-7302-4922
Anna A BurianDepartment of Pharmaceutical Chemistry, National University of Pharmacy, 53 Pushkinska st., 61002 Kharkiv, Ukraine. anna_chem@ukr.net.
Vyacheslav N BaumerSSI "Institute for Single Crystals", National Academy of Sciences of Ukraine, 60 Nauki ave., 61001 Kharkiv, Ukraine. baumer@xray.isc.kharkov.com.
Svitlana V ShishkinaSSI "Institute for Single Crystals", National Academy of Sciences of Ukraine, 60 Nauki ave., 61001 Kharkiv, Ukraine. sveta@xray.isc.kharkov.com.
Lyudmila V SidorenkoDepartment of Pharmaceutical Chemistry, National University of Pharmacy, 53 Pushkinska st., 61002 Kharkiv, Ukraine. slv.ludmila@i.ua.ORCID 0000-0001-8431-8398
Igor A TugaibeiDepartment of Clinical Biochemistry, Forensic Toxicology, and Pharmacy, Kharkiv Medical Academy of Postgraduate Education, 58 Amosov st., 61176 Kharkiv, Ukraine. igor_doctor@rambler.ru.
Natali I VoloshchukDepartment of Pharmacology, N. I. Pirogov Vinnitsa National Medical University, 56 Pirogov st., 21018 Vinnitsa, Ukraine. voloshchuknatali@gmail.com.ORCID 0000-0002-0166-9676
Pavlo S BondarenkoDepartment of Pharmacology, N. I. Pirogov Vinnitsa National Medical University, 56 Pirogov st., 21018 Vinnitsa, Ukraine. bondarenkopavel1506@gmail.com.
National University of Pharmacy · UANational Academy of Sciences of Ukraine · UANational Pirogov Memorial Medical University, Vinnytsya · UAKharkiv Medical Academy of Postgraduate Education · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuing the search for new potential analgesics among the derivatives of 4-methyl-2,2-dioxo-1

Indexed as

2,1-benzothiazine4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acidalkylationanalgesic activityanti-inflammatory actioncrystal structureesterspolymorphism

Identifiers

PMID29848976
PMCPMC6027672
OpenAlexW2806720473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.