Evidence map›Paper›PMID 29848923›Full record

ArticleAnatolian journal of cardiology2018

Speckle-tracking strain assessment of left ventricular dysfunction in synthetic cannabinoid and heroin users.

Aykut Demirkıran, Neslihan Albayrak, Yakup Albayrak, Cafer Sadık Zorkun

Open access · diamondAbstract read
In one paragraph

Article in Anatolian journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Effect of Heroin on Electrocardiographic Parameters.Arquivos brasileiros de cardiologia · 2020
    Article
  4. Strain can hide some states.Anatolian journal of cardiology · 2018
    Article
  5. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aykut DemirkıranDepartment of Cardiology, Tekirdağ Çorlu State Hospital; Tekirdağ-Turkey. aykut_wax@hotmail.com.
Neslihan Albayrak
Yakup Albayrak
Cafer Sadık Zorkun
State Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is growing evidence regarding the numerous adverse effects of synthetic cannabinoids (SCBs) on the cardiovascular system; however, no studies have shown the cardiovascular effects of opioids using strain echocardiography. This study examines the cardiac structure and function using echocardiographic strain imaging in heroin and synthetic cannabinoid users.

methodsThis double-blind study included patients who were admitted or referred to a rehabilitation center for heroin (n=31) and synthetic cannabinoid users (n=30). Heroin users and synthetic cannabinoid users were compared with healthy volunteers (n=32) using two-dimensional (2D) speckle-tracking (ST) echocardiography.

resultsNo differences were found in the baseline characteristics and 2D echocardiography values. The mean global longitudinal strain value was -20.5%±2.4% for SCB users, -22.3%±2.4% for opioid users, and -22.5%±2.2% for healthy volunteers (p=0.024). The mean apical 2-chamber (AP2C) L-strain values were -20.1%±3.1%, -22.4%±3.0%, and -22.3%±2.8% for SCB users, opioid users, and healthy volunteers, respectively (p=0.032). The mean apical 4-chamber (AP4C) L-strain values were -20.7%±2.5% for SCB users, -23.2%±3.2% for opioid users, and -23.8%±3.1% for healthy volunteers (p<0.001).

conclusionSCBs are potential causes of subclinical left ventricular dysfunction.

Indexed as

CannabinoidsCase-Control StudiesDouble-Blind MethodEchocardiographyFemaleHeroinHumansMaleProspective StudiesSensitivity and SpecificitySubstance-Related DisordersVentricular Dysfunction, LeftYoung AdultCannabinoidsHeroin

Identifiers

PMID29848923
PMCPMC5998859
OpenAlexW2799902135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.