Evidence map›Paper›PMID 29848759›Full record

ArticlemSphere2018

Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression

Georgia Wilke, Soumya Ravindran, Lisa Funkhouser-Jones, Jennifer Barks, Qiuling Wang, Kelli L VanDussen, Thaddeus S Stappenbeck, Theresa B Kuhlenschmidt, Mark S Kuhlenschmidt, L David Sibley

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  4. Article
  5. Early life infection withGut microbes · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Georgia Wilke *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Soumya Ravindran *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Lisa Funkhouser-Jones *Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Jennifer BarksDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Qiuling WangDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Kelli L VanDussenDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Thaddeus S StappenbeckDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Theresa B KuhlenschmidtDepartment of Pathobiology, University of Illinois College of Veterinary Medicine, Urbana, Illinois, USA.
Mark S KuhlenschmidtDepartment of Pathobiology, University of Illinois College of Veterinary Medicine, Urbana, Illinois, USA.
L David SibleyDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA sibley@wustl.edu.
Washington University in St. Louis · USUniversity of Illinois Urbana-Champaign · US

Funding

Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Viral Discovery in Rheumatoid ArthritisP30AR048335 · NIAMS · WASHINGTON UNIVERSITY · PI BYUN, MINJI · 2001 to 2015
$8.9M
DEFINING THE BASIS OF EPITHELIAL DEFECTS IN CROHN'S DISEASE PATIENTSK01DK109081 · NIDDK · WASHINGTON UNIVERSITY · PI VANDUSSEN, KELLI LYNN · 2016 to 2020
$737k
NIAID NIH HHS T32 AI007172NIAMS NIH HHS P30 AR048335NIDDK NIH HHS K01 DK109081
6 · The paper itself

Abstract

Among the obstacles hindering

Indexed as

Life Cycle StagesAnimalsAntibodies, MonoclonalAntibodies, ProtozoanAntigens, ProtozoanCell LineCryptosporidium parvumEpithelial CellsMiceOptical ImagingStaining and LabelingAntibodies, MonoclonalAntibodies, ProtozoanAntigens, ProtozoanCryptosporidiumcytoskeletonintracellular parasitesmembrane proteinsmonoclonal antibodiessexual development

Identifiers

PMID29848759
PMCPMC5976880
OpenAlexW2806169927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.