Evidence map›Paper›PMID 29848586›Full record

ArticleJournal of virology2018

Smc5/6 Antagonism by HBx Is an Evolutionarily Conserved Function of Hepatitis B Virus Infection in Mammals.

Fabien Abdul, Fabien Filleton, Laetitia Gerossier, Alexia Paturel, Janet Hall, Michel Strubin, Lucie Etienne

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  13. Genome control by SMC complexes.Nature reviews. Molecular cell biology · 2023
    Review
  14. Review
  15. Smc5/6 silences episomal transcription by a three-step function.Nature structural & molecular biology · 2022
    Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fabien Abdul *Department of Microbiology and Molecular Medicine, University Medical Centre (CMU)/University of Geneva, Geneva, Switzerland.
Fabien Filleton *CIRI-International Center for Infectiology Research, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Lyon, Lyon, France.
Laetitia GerossierCRCL-UMR Inserm 1052-CNRS 5286, Lyon, France.
Alexia PaturelCRCL-UMR Inserm 1052-CNRS 5286, Lyon, France.
Janet HallCRCL-UMR Inserm 1052-CNRS 5286, Lyon, France.
Michel StrubinDepartment of Microbiology and Molecular Medicine, University Medical Centre (CMU)/University of Geneva, Geneva, Switzerland.
Lucie EtienneCIRI-International Center for Infectiology Research, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Lyon, Lyon, France lucie.etienne@ens-lyon.fr.ORCID https://orcid.org/0000-0002-8585-7534
Centre National de la Recherche Scientifique · FRUniversité Claude Bernard Lyon 1 · FRUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic infection with hepatitis B virus (HBV) is a major cause of liver disease and cancer in humans. HBVs (family

Indexed as

Host-Pathogen InteractionsAnimalsCell Cycle ProteinsEvolution, MolecularGenetic VariationHepatitis B virusMammalsPhylogenyProteolysisTrans-ActivatorsViral Regulatory and Accessory ProteinsCell Cycle Proteinshepatitis B virus X proteinTrans-ActivatorsViral Regulatory and Accessory Proteinsantagonismevolution of virus and host genesHBxhepatitis B viruspositive selectionrestriction factorSmc5/6 complexvirus-host interaction

Identifiers

PMID29848586
PMCPMC6069175
OpenAlexW2953350994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.