Evidence map›Paper›PMID 29848569›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention.

Maeve A Lowery, Ryan Ptashkin, Emmet Jordan, Michael F Berger, Ahmet Zehir, Marinela Capanu, Nancy E Kemeny, Eileen M O'Reilly, Imane El-Dika, William R Jarnagin and 10 more

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 341 papers.

0numbers the graph read from it
0cells of the map it votes in
341citing papers in PubMed
45.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

341 citing papers in PubMed, 565 citations in OpenAlex.

  1. Efficacy and Tolerability of Zenocutuzumab in AdvancedJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
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  5. Evaluating Debio 1347 in Patients with FGFR Fusion-Positive Advanced Solid Tumors from the FUZE Multicenter, Open-Label, Phase II Basket Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Trial
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  8. Review
  9. Article
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  13. Article
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  15. Molecular and Clinical Determinants of Targeted Therapy Treatment in Biliary Tract Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  16. Review
  17. Review
  18. Prognostic Impact of Concomitant Genomic Alterations in FGFR2-Positive Cholangiocarcinoma Treated With Pemigatinib.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  19. Article
  20. Article

281 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 2 countries.

Maeve A LoweryTrinity College Dublin, Dublin, Ireland.
Ryan PtashkinMemorial Sloan Kettering Cancer Center, New York, New York.
Emmet JordanMemorial Sloan Kettering Cancer Center, New York, New York.
Michael F BergerMemorial Sloan Kettering Cancer Center, New York, New York.
Ahmet ZehirMemorial Sloan Kettering Cancer Center, New York, New York.
Marinela CapanuMemorial Sloan Kettering Cancer Center, New York, New York.
Nancy E KemenyMemorial Sloan Kettering Cancer Center, New York, New York.
Eileen M O'ReillyMemorial Sloan Kettering Cancer Center, New York, New York.
Imane El-DikaMemorial Sloan Kettering Cancer Center, New York, New York.
William R JarnaginMemorial Sloan Kettering Cancer Center, New York, New York.
James J HardingMemorial Sloan Kettering Cancer Center, New York, New York.
Michael I D'AngelicaMemorial Sloan Kettering Cancer Center, New York, New York.
Andrea CercekMemorial Sloan Kettering Cancer Center, New York, New York.
Jaclyn F HechtmanMemorial Sloan Kettering Cancer Center, New York, New York.
David B SolitMemorial Sloan Kettering Cancer Center, New York, New York.
Nikolaus SchultzMemorial Sloan Kettering Cancer Center, New York, New York.
David M HymanMemorial Sloan Kettering Cancer Center, New York, New York.
David S KlimstraMemorial Sloan Kettering Cancer Center, New York, New York.
Leonard B SaltzMemorial Sloan Kettering Cancer Center, New York, New York.
Ghassan K Abou-AlfaMemorial Sloan Kettering Cancer Center, New York, New York. abou-alg@mskcc.org.ORCID 0000-0002-1522-8054
Memorial Sloan Kettering Cancer Center · USTrinity College Dublin · IE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overBiomarkers, TumorCholangiocarcinomaCyclin-Dependent Kinase Inhibitor p15Cyclin-Dependent Kinase Inhibitor p16Disease-Free SurvivalDNA-Binding ProteinsErb-b2 Receptor Tyrosine KinasesExonsFemaleHigh-Throughput Nucleotide SequencingHumansIntronsIsocitrate DehydrogenaseARID1A protein, humanBAP1 protein, humanBiomarkers, TumorCDKN2A protein, humanCDKN2B protein, humanCyclin-Dependent Kinase Inhibitor p15Cyclin-Dependent Kinase Inhibitor p16DNA-Binding ProteinsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFGFR2 protein, humanIDH1 protein, humanIsocitrate DehydrogenaseKRAS protein, humanNuclear ProteinsOncogene Proteins, FusionProto-Oncogene Proteins p21(ras)Receptor, Fibroblast Growth Factor, Type 2TP53 protein, humanTranscription FactorsTumor Suppressor Protein p53Tumor Suppressor ProteinsUbiquitin Thiolesterase

Identifiers

PMID29848569
PMCPMC6642361
OpenAlexW2806800293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.