Evidence map›Paper›PMID 29848553›Full record

ArticleOccupational and environmental medicine2018

Exposure, respiratory symptoms, lung function and inflammation response of road-paving asphalt workers.

Yiyi Xu, Monica Kåredal, Jörn Nielsen, Mariana Adlercreutz, Ulf Bergendorf, Bo Strandberg, Ann-Beth Antonsson, Håkan Tinnerberg, Maria Albin

Open access · hybridAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yiyi XuDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.ORCID 0000-0001-9106-0049
Monica KåredalDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Jörn NielsenDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Mariana AdlercreutzDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Ulf BergendorfDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Bo StrandbergDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Ann-Beth AntonssonIVL Swedish Environmental Research Institute, Stockholm, Sweden.
Håkan TinnerbergDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Maria AlbinDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Lund University · SEIVL Swedish Environmental Research Institute · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControversy exists as to the health effects of exposure to asphalt and crumb rubber modified (CRM) asphalt, which contains recycled rubber tyres.

objectiveTo assess exposures and effects on airway symptoms, lung function and inflammation biomarkers in conventional and CRM asphalt road pavers.

methods116 conventional asphalt workers, 51 CRM asphalt workers and 100 controls were investigated. A repeated-measures analysis included 31 workers paving with both types of asphalt. Exposure to dust, nitrosamines, benzothiazole and polycyclic aromatic hydrocarbon (PAH) was measured in worksites. Self-reported symptoms, spirometry test and blood sampling were conducted prework and postwork. Symptoms were further collected during off-season for asphalt paving.

resultsDust, PAHs and nitrosamine exposure was highly varied, without difference between conventional and CRM asphalt workers. Benzothiazole was higher in CRM asphalt workers (p<0.001). Higher proportions of asphalt workers than controls reported eye symptoms with onset in the current job. Decreased lung function from preworking to postworking was found in CRM asphalt workers and controls. Preworking interleukin-8 was higher in CRM asphalt workers than in the controls, followed by a decrement after 4 days of working. No differences in any studied effects were found between conventional and CRM asphalt paving.

conclusionCRM asphalt workers are exposed to higher benzothiazole. Further studies are needed to identify the source of nitrosamines in conventional asphalt. Mild decrease in lung function in CRM asphalt workers and work-related eye symptoms in both asphalt workers were observed. However, our study did not find strong evidence for severe respiratory symptoms and inflammation response among asphalt workers.

Indexed as

HydrocarbonsInflammationOccupational ExposureOccupationsRespiratory Tract DiseasesRubberAdultAir Pollutants, OccupationalBenzothiazolesBiomarkersDustEyeHumansInhalation ExposureInterleukin-8LungAir Pollutants, OccupationalasphaltBenzothiazolesBiomarkersDustHydrocarbonsInterleukin-8NitrosaminesPolycyclic Aromatic HydrocarbonsRubberasphaltC-reactive proteininterleukinlung function testoccupational exposurerespiratory symptomsrubber asphalt

Identifiers

PMID29848553
PMCPMC6035487
OpenAlexW2806678347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.