Evidence map›Paper›PMID 29848540›Full record

ArticleBMJ case reports2018

Pulmonary embolism and infarction with a paradoxical thrombus visualised in both atria.

Hamza Zafar, Lisa Anderson, Andrew T Cox, Rachel Bastiaenen

Open access · greenAbstract readCase ReportsVideo-Audio Media
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Neurological Complications of Pulmonary Embolism: a Literature Review.Current neurology and neuroscience reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hamza ZafarCardiology Clinical Academic Group, St Georges University Hospitals NHS Trust, London, UK.ORCID http://orcid.org/0000-0002-9599-1534
Lisa AndersonCardiology Clinical Academic Group, St Georges University Hospitals NHS Trust, London, UK.
Andrew T CoxCardiology Clinical Academic Group, St Georges University Hospitals NHS Trust, London, UK.
Rachel BastiaenenCardiology Clinical Academic Group, St Georges University Hospitals NHS Trust, London, UK.
St George’s University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 59-year-old woman presented with a sudden onset of breathlessness and chest pain. An echocardiography and CT scan showed pulmonary embolism and infarction with a paradoxical thrombus visualised in both atria. For haemodynamically stable patients, the optimal management strategy is poorly defined. Three main strategies were considered: surgical thrombectomy, thrombolysis and anticoagulation. Surgery with reversal of anticoagulation may lead to further coagulation and increased risk of bleeding complications. The significant pulmonary hypertension and right ventricular infarction raised the prospect of difficult weaning from cardiopulmonary bypass following thrombectomy. Thrombolysis, which has significant mortality rate, and systemic embolisation including pulmonary infarction with haemorrhagic transformation were also contraindications. A multidisciplinary approach was adopted and anticoagulation was therefore believed to be the safest and effective approach. Here, the use of anticoagulation alone was fortunately successful but could as easily end in disaster. This approach should be considered the ideal paradigm to yield optimum outcomes.

Indexed as

AnticoagulantsComputed Tomography AngiographyDrug Therapy, CombinationEmbolism, ParadoxicalFemaleHeart AtriaHeart DiseasesHeparinHumansMiddle AgedPulmonary EmbolismPulmonary InfarctionThrombosisTreatment OutcomeWarfarinAnticoagulantsHeparinWarfarincardiovascular medicinevenous thromboembolism

Identifiers

PMID29848540
PMCPMC5976082
OpenAlexW2805686501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.