ArticleJournal of the American Heart Association2018
Risk Prediction of Atrial Fibrillation Based on Electrocardiographic Interatrial Block.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05084495 (Can Global Peak Longitudinal Strain Measurements in Combination With Non-invasive ECG Parameters Predict the Success or Failure of Flecainide Treatment for Atrial Fibrillation Patients?), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Global Peak Longitudinal Strain Measurements in Combination With Non-invasive ECG Parameters Predict the Success or Failure of Flecainide Treatment for Atrial Fibrillation Patients?
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Predicting risk of AF in ischaemic stroke using sinus rhythm ECG abnormalities: A meta-analysis.European stroke journal · 2023Pooled it
- Electrocardiographic Predictors of Atrial Fibrillation.Medical sciences (Basel, Switzerland) · 2023Pooled it
- Risk of atrial fibrillation according to electrocardiographic risk factors: a nationwide cohort study of 1.5 million patients.European heart journal open · 2026Article
- Predictive factors for new-onset atrial fibrillation in patients with embolic stroke of undetermined source and left atrial enlargement - development of a risk score.Cardiology journal · 2026Observational
- The Effect of Iron Deficiency Anemia on the Morphology-Voltage-P Wave Duration (MVP) Risk Score.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025Article
- Interatrial Block Detected by a Series of ECGs Before and During Acute Coronary Syndrome Predicts Atrial Fibrillation, Atrial Flutter, and Ischemic Stroke.Journal of the American Heart Association · 2025Article
- New-Onset Atrial Fibrillation During ST-Segment-Elevation Myocardial Infarction: Risk of Recurrence and Its Clinical Impact During 10 Years of Follow-Up.Journal of the American Heart Association · 2025Article
- Association of P-wave characteristics with long-standing atrial high rate episodes (AHREs) following pacemaker implantation.BMC cardiovascular disorders · 2025Article
- The Impacts of Housing Conditions on the Cardiopulmonary and Neurobehavioral Responses of Mice to High Temperature and Wildfire Smoke.Environmental science & technology · 2025Article
- Inter-atrial block as a predictor of adverse outcomes in patients with HFpEF.ESC heart failure · 2025Article
- Preoperative interatrial block is associated with postoperative atrial fibrillation after cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Survey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine.NPJ digital medicine · 2025Review
- Interatrial block is an independent risk factor for new-onset atrial fibrillation after cardiac surgery.JTCVS open · 2024Article
- Association of abnormal P-wave parameters with all-cause mortality in diffuse large B-cell lymphoma.Scientific reports · 2024Article
- The Role of P Wave Parameters in Predicting Pulmonary Vein Isolation Outcomes for Paroxysmal Atrial Fibrillation: An Observational Cohort Study.Journal of cardiovascular development and disease · 2024Article
- Advanced Interatrial Block across the Spectrum of Renal Function.Medicina (Kaunas, Lithuania) · 2024Article
- Simple risk scoring using sinus rhythm electrocardiograms predicts the incidence of atrial fibrillation in the general population.Scientific reports · 2024Article
- Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- The prognostic role of interatrial block among COVID-19 patients hospitalized in medicine wards.European journal of clinical investigation · 2022Article
- P Wave Parameters and Indices: A Critical Appraisal of Clinical Utility, Challenges, and Future Research-A Consensus Document Endorsed by the International Society of Electrocardiology and the International Society for Holter and Noninvasive Electrocardiology.Circulation. Arrhythmia and electrophysiology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe electrocardiographic interatrial block (IAB) has been associated with atrial fibrillation (AF). We aimed to test whether IAB can improve risk prediction of AF for the individual person. METHODS AND
resultsDigital ECGs of 152 759 primary care patients aged 50 to 90 years were collected from 2001 to 2011. We identified individuals with P-wave ≥120 ms and the presence of none, 1, 2, or 3 biphasic P-waves in inferior leads. Data on comorbidity, medication, and outcomes were obtained from nationwide registries. We observed a dose-response relationship between the number of biphasic P-waves in inferior leads and the hazard of AF during follow-up. Discrimination of the 10-year outcome of AF, measured by time-dependent area under the curve, was increased by 1.09% (95% confidence interval 0.43-1.74%) for individuals with cardiovascular disease at baseline (CVD) and 1.01% (95% confidence interval 0.40-1.62%) for individuals without CVD, when IAB was added to a conventional risk model for AF. The highest effect of IAB on the absolute risk of AF was observed in individuals aged 60 to 70 years with CVD. In this subgroup, the 10-year risk of AF was 50% in those with advanced IAB compared with 10% in those with a normal P-wave. In general, individuals with advanced IAB and no CVD had a higher risk of AF than patients with CVD and no IAB.
conclusionsIAB improves risk prediction of AF when added to a conventional risk model. Clinicians may consider monitoring patients with IAB more closely for the occurrence of AF, especially for high-risk subgroups.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.