Evidence map›Paper›PMID 29848401›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Extent and Dynamics of Polymorphism in the Malaria Vaccine Candidate

Amed Ouattara, Tuan M Tran, Safiatou Doumbo, Matthew Adams, Sonia Agrawal, Amadou Niangaly, Sara Nelson-Owens, Didier Doumtabé, Youssouf Tolo, Aissata Ongoiba and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. The N-terminal region of malaria vaccine candidatebioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Hotspots inInternational journal of molecular sciences · 2020
    Review
  12. Article
  13. Potential ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Amed OuattaraMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Tuan M TranLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.
Safiatou DoumboMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Matthew AdamsDivision of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, Baltimore, Maryland.
Sonia AgrawalDivision of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, Baltimore, Maryland.
Amadou NiangalyMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Sara Nelson-OwensSchool of Medicine, Meharry Medical College, Nashville, Tennessee.
Didier DoumtabéMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Youssouf ToloMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Aissata OngoibaMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Shannon Takala-HarrisonDivision of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, Baltimore, Maryland.
Boubacar TraoréMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Joana C SilvaInstitute for Genome Sciences, University of Maryland Baltimore, Baltimore, Maryland.
Peter D CromptonLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.
Ogobara K DoumboMalaria Research and Training Center, University of Sciences, Techniques and Technology, Bamako, Mali.
Christopher V PloweDuke University, Durham North Carolina.
University of Bamako · MLUniversity of Maryland, Baltimore · USDuke University · USIndiana University – Purdue University Indianapolis · USMeharry Medical College · USNational Institutes of Health · US

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI WHITE, OWEN R · 2014 to 2023
$36.5M
Mechanisms of naturally-acquired immunity to malaria and clinical trials of anti-malaria monoclonal antibodiesZIAAI001155 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CROMPTON, PETER · 2011 to 2025
$30.9M
NIAID NIH HHS U19 AI110820
6 · The paper itself

Abstract

Reticulocyte-binding homologues (RH) are a ligand family that mediates merozoite invasion of erythrocytes in

Indexed as

HaplotypesPolymorphism, GeneticAdolescentAdultAmino Acid SequenceB-LymphocytesCarrier ProteinsChildChild, PreschoolEpitopes, B-LymphocyteEpitopes, T-LymphocyteErythrocytesFemaleGene ExpressionHumansInfantCarrier ProteinsEpitopes, B-LymphocyteEpitopes, T-LymphocyteMalaria VaccinesPeptidesRH5 protein, Plasmodium falciparum

Identifiers

PMID29848401
PMCPMC6085788
OpenAlexW2806583249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.