ArticlePloS one2018
Exogenous dietary enzyme formulations improve growth performance of broiler chickens fed a low-energy diet targeting the intestinal nutrient transporter genes.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Meta-analysis of substitution value of maize with cassava (Frontiers in veterinary science · 2022Pooled it
- Dietary supplementation of endo-1,4-ß-D-mannanase improves turkey growth through enhancement of immune response and jejunal barrier integrity.Poultry science · 2026Article
- Enzyme-assisted valorization of agro-industrial byproducts for sustainable and efficient broiler production.Veterinary world · 2026Review
- Far-infrared ray and β-mannanase influence on growth performance, meat quality, gut morphology, and blood parameters in nutritionally challenged broilers.Journal of animal science and technology · 2026Article
- Nutrient transporters in broiler chickens: intestinal gene expression profiles, functional roles, and influencing factors.Journal of animal science and biotechnology · 2025Review
- Betaine alleviates hepatic lipid metabolism disorder in finishing pigs fed a low-energy diet through regulating mJournal of animal science and biotechnology · 2025Article
- Dietary ginger (Animal biotechnology · 2024Article
- Quantification of toxic metals in chicken egg and chicken feed via SOM-artificial neural network.Environmental monitoring and assessment · 2024Article
- Dietary lysozyme and avilamycin modulate gut health, immunity, and growth rate in broilers.BMC veterinary research · 2024Article
- Effects of dietary multienzymes on the growth performance, digestive enzyme activity, nutrient digestibility, excreta noxious gas emission, and nutrient transporter gene expression in white feather broilers.Journal of animal science · 2024Article
- Impacts of Solid-State Fermented Barley with Fibrolytic Exogenous Enzymes on Feed Utilization, and Antioxidant Status of Broiler Chickens.Veterinary sciences · 2023Article
- Nutritional Strategies to Improve Meat Quality and Composition in the Challenging Conditions of Broiler Production: A Review.Animals : an open access journal from MDPI · 2023Review
- Growth performance, blood lipids, and fat digestibility of broilers fed diets supplemented with bile acid and xylanase.Archives animal breeding · 2023Article
- Effect of Exogenous Enzymes Cocktail on Performance, Carcass Traits, Biochemical Metabolites, Intestinal Morphology, and Nutrient Digestibility of Broilers Fed Normal and Low-Energy Corn-Soybean Diets.Animals : an open access journal from MDPI · 2022Article
- Impact of Feeding Fermented Palm Kernel Cake and High Dietary Fat on Nutrient Digestibility, Enzyme Activity, Intestinal Morphology and Intestinal Nutrient Transporters mRNA Expression in Broiler Chickens under Hot and Humid Conditions.Animals : an open access journal from MDPI · 2022Article
- Article
- Modulatory effect of dietary probiotic and prebiotic supplementation on growth, immuno-biochemical alterations, DNA damage, and pathological changes inFrontiers in veterinary science · 2022Article
- Different enzymatic associations in diets of broiler chickens formulated with corn dried at various temperatures.Poultry science · 2021Article
- Effect of Bacterial or Fungal Phytase Supplementation on the Performance, Egg Quality, Plasma Biochemical Parameters, and Reproductive Morphology of Laying Hens.Animals : an open access journal from MDPI · 2021Article
- Progress on Gut Health Maintenance and Antibiotic Alternatives in Broiler Chicken Production.Frontiers in nutrition · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diminishing the cost of broiler chicken diet is a critical issue in the poultry industry. Numerous studies were performed to achieve this pivotal objective by diet supplementation with alternative feed additives. In the current study, low-energy broiler rations were supplemented with different commercial multienzyme formulations to minimize the cost, and increase the digestibility and absorption of the digested macronutrients. Cobb Avian 48 broiler chicks (mixed sex, 1-d-old, n = 3120) were randomly allocated into six groups, and each group was subdivided into four replicates (130 birds per replicate). The birds were randomly allocated into a control group fed basal diet (CB); control group fed low-energy diet (CL); and birds fed low-energy diets supplemented with different enzyme formulations. The enzyme formulations used were Xylam 500® (CLX group), Hemicell® (CLH group), Avizyme® (CLA group), and Megazyme® (CLM group,) following the doses recommended by the manufacturers. The growth performance of CLA and CLH group birds was significantly improved when compared with CL. In comparison with CB, Avizyme® significantly (p < 0.001) increased the intestinal PEPT1, GLUT2, ACC, and IL-2 expression; PEPT1 facilitates the absorption of micronutrients. In conclusion, exogenous multienzyme complexes may be included in the low-energy diet to enhance the performance of broiler chickens (Avizyme® ˃ Hemicell® ˃ Megazyme®), and reduce the diet cost by up-regulating the expression of intestinal nutrient transporter genes, and improving the immunity and serum biochemical parameters of broiler chickens.
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Registered trials
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