Evidence map›Paper›PMID 29847236›Full record

ArticleJournal of neurophysiology2018

Na

Tyler L Marler, Andrew B Wright, Kristina L Elmslie, Ankeeta K Heier, Ethan Remily, Jeong Sook Kim-Han, Renuka Ramachandra, Keith S Elmslie

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. NaJournal of neurophysiology · 2022
    Article
  3. Article
  4. Enhancement by TNF-α of TTX-resistant NaAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tyler L MarlerThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Andrew B WrightThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Kristina L ElmslieThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Ankeeta K HeierThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Ethan RemilyThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Jeong Sook Kim-HanThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Renuka RamachandraThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
Keith S ElmslieThe Baker Laboratory of Pharmacology, Department of Pharmacology, Kirksville College of Osteopathic Medicine, A. T. Still University of Health Sciences, Kirksville, Missouri.
A.T. Still University · US

Funding

Excitability of Afferents Evoking the Exercise Pressor ReflexR01AR059397 · NIAMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI ELMSLIE, KEITH S, KAUFMAN, MARC PETER · 2010 to 2019
$5.4M
NIAMS NIH HHS R01 AR059397
6 · The paper itself

Abstract

The exercise pressor reflex (EPR) is activated by muscle contractions to increase heart rate and blood pressure during exercise. While this reflex is beneficial in healthy individuals, the reflex activity is exaggerated in patients with cardiovascular disease, which is associated with increased mortality. Group III and IV afferents mediate the EPR and have been shown to express both tetrodotoxin-sensitive (TTX-S, Na

Indexed as

Action PotentialsAniline CompoundsAnimalsAxonsFuransGanglia, SpinalImmunohistochemistryMaleMicroscopy, FluorescenceMuscle ContractionMuscle, SkeletalNAV1.9 Voltage-Gated Sodium ChannelNeurons, AfferentNormal DistributionPatch-Clamp TechniquesRatsA 803467Aniline CompoundsFuransNAV1.9 Voltage-Gated Sodium ChannelSodium Channel BlockersA803467axon channelsexercise pressor refleximmunohistochemistrypatch clamp

Identifiers

PMID29847236
PMCPMC6171062
OpenAlexW2806707906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.