Trial reportLasers in medical science2018
A randomized controlled trial comparing helium-neon laser therapy and infrared laser therapy in patients with diabetic foot ulcer.
Trial report in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Effects and parameterization of low-level laser therapy in diabetic ulcers: an umbrella review of systematic reviews and meta-umbrella.Lasers in medical science · 2025Pooled it
- Dose-response and efficacy of 660-nanometer low-level laser therapy in healing diabetic foot ulcers: a randomized, double-blind, clinical trial.Lasers in medical science · 2025Trial
- Short-term clinical efficacy of the pulsed Nd: YAG laser therapy on chronic nonspecific low back pain: A randomized controlled study.Medicine · 2020Trial
- Laser photobiomodulation is more effective than ultrasound therapy in patients with chronic nonspecific low back pain: a comparative study.Lasers in medical science · 2019Trial
- Therapeutic Effects of Photobiomodulation Combined with Exercise on Patients with Peripheral Artery Disease Plus Diabetic Foot Ulcer: A Pilot and Feasibility Study.Life (Basel, Switzerland) · 2025Article
- Electromechanical therapy in diabetic foot ulcers patients: A systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2023Review
- Unveiling Therapeutic Potential: A Systematic Review of Photobiomodulation Therapy and Biological Dressings for Diabetic Foot Ulcers.Journal of lasers in medical sciences · 2023Review
- TECAR Therapy Associated with High-Intensity Laser Therapy (Hilt) and Manual Therapy in the Treatment of Muscle Disorders: A Literature Review on the Theorised Effects Supporting Their Use.Journal of clinical medicine · 2022Review
- Clinical Effect of Photobiomodulation on Wound Healing of Diabetic Foot Ulcers: Does Skin Color Needs to Be Considered?Journal of diabetes research · 2022Review
- Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment.Disease markers · 2022Article
- Low-Level Laser Therapy for Diabetic Dermopathy in Patients With Type 2 Diabetes: A Placebo-Controlled Pilot Study.Journal of lasers in medical sciences · 2020Article
- A Randomized Comparative Study between High-Intensity and Low-Level Laser Therapy in the Treatment of Chronic Nonspecific Low Back Pain.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Auto-Administered Photobiomodulation on Diabetic Leg Ulcers Treatment: A New Way to Manage It?Case reports in medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to compare the effects of (HNLT) and (ILT) on diabetic foot ulcer. Sixty-five patients with diabetic foot ulcer (51 males and 14 females) aged 50-60 years. The participants were classified randomly to two groups, groups I and II. Group I received helium-neon laser therapy (HNLT) and conventional therapy with and group II received infrared laser therapy (ILT) and conventional therapy with for 8 weeks. Ulcer surface area was assessed using a sheet of cellophane paper at the beginning of the study, after 4 weeks, and after 8 weeks at the end of the study. At the beginning of the study, baseline clinical characteristics showed non-significant differences between the two groups (p > 0.05). After 4 weeks intervention, there were significant improvements in ulcer surface area in the two groups (p < 0.05). At the end of the study, after 8 weeks intervention, there were higher reduction in ulcer area in HNLT group more than ILT group, but this difference was statistically non- significant between the two groups (p > 0.05). The present study demonstrates that HNLT and ILT have similar effects to control diabetic foot ulcer in a short-term (up to 8 weeks). Eight weeks of laser therapy have beneficial impacts in diabetic foot ulcer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.