Evidence map›Paper›PMID 29846828›Full record

ReviewCurrent rheumatology reports2018

CNS Vasculitis: an Approach to Differential Diagnosis and Management.

Kevin Byram, Rula A Hajj-Ali, Leonard Calabrese

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Tumor-mimicking primary CNS vasculitis: illustrative case.Journal of neurosurgery. Case lessons · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Primary CNS Vasculitis - A Focussed Review on Treatment.Vascular health and risk management · 2024
    Review
  9. Article
  10. Advances in Management of the Stroke Etiology One-Percenters.Current neurology and neuroscience reports · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Localized Forms of Vasculitis.Current rheumatology reports · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kevin ByramDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, T3113, MCN, Nashville, TN, 37232, USA. byramk@ccf.org.
Rula A Hajj-AliCleveland Clinic Center for Vasculitis Care and Research, 9500 Euclid Ave, A50, Cleveland, OH, 44195, USA.
Leonard CalabreseCleveland Clinic Center for Vasculitis Care and Research, 9500 Euclid Ave, A50, Cleveland, OH, 44195, USA. Calabrl@ccf.org.
Cleveland Clinic · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe goal of this review is to provide an up-to-date approach to diagnosis and management of patients with central nervous system (CNS) vasculitis. RECENT

findingsChallenges in diagnosis of CNS vasculitis still exist due to the broad differential diagnosis and generally nonspecific initial clinical manifestations. Differentiation between primary angiitis of the CNS (PACNS) and secondary causes is important in guiding management. Recent longitudinal cohort studies have improved our understanding of PACNS. Advances in neuroimaging and molecular testing have enhanced diagnostic decision-making. Therapy remains largely empiric, guided by observational data. Despite the limited use of targeted therapies, glucocorticoids and cyclophosphamide remain the mainstays of therapy in PACNS. Securing a diagnosis through a careful, team-based approach with emphasis on ruling out possible mimics is paramount in the management of patients with CNS vasculitis.

Indexed as

CyclophosphamideDiagnosis, DifferentialGlucocorticoidsHumansImmunosuppressive AgentsVasculitis, Central Nervous SystemCyclophosphamideGlucocorticoidsImmunosuppressive AgentsCNS vasculitisPrimary angiitis of the central nervous systemPrimary central nervous system vasculitisPrimary CNS vasculitis

Identifiers

PMID29846828
OpenAlexW2805944140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.