Evidence map›Paper›PMID 29845771›Full record

ArticlePhysiological reports2018

Cerebellar direct current stimulation modulates hand blink reflex: implications for defensive behavior in humans.

Tommaso Bocci, Roberta Ferrucci, Davide Barloscio, Laura Parenti, Francesca Cortese, Alberto Priori, Ferdinando Sartucci

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Tommaso BocciDepartment of Clinical and Experimental Medicine, Cisanello Neurology Unit, Pisa University Medical School, Pisa, Italy.
Roberta FerrucciDepartment of Medical-Surgical Pathophysiology and Transplants, University of Milan, Milan, Italy.
Davide BarloscioDepartment of Clinical and Experimental Medicine, Cisanello Neurology Unit, Pisa University Medical School, Pisa, Italy.
Laura ParentiDepartment of Clinical and Experimental Medicine, Cisanello Neurology Unit, Pisa University Medical School, Pisa, Italy.
Francesca CorteseDepartment of Medical-Surgical Pathophysiology and Transplants, University of Milan, Milan, Italy.
Alberto PrioriDepartment of Medical-Surgical Pathophysiology and Transplants, University of Milan, Milan, Italy.
Ferdinando SartucciDepartment of Clinical and Experimental Medicine, Cisanello Neurology Unit, Pisa University Medical School, Pisa, Italy.
Ospedale Cisanello · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITSapienza University of Rome · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebellum is involved in a wide number of integrative functions. We evaluated the role of cerebellum in peripersonal defensive behavior, as assessed by the so-called hand blink reflex (HBR), modulating cerebellar activity with transcranial direct current stimulation (tDCS). Healthy subjects underwent cerebellar (sham, anodal, and cathodal tcDCS) and motor cortex tDCS (anodal or cathodal; 20', 2 mA). For the recording of HBR, electrical stimuli were delivered using a surface bipolar electrode placed on the median nerve at the wrist and EMG activity recorded from the orbicularis oculi muscle bilaterally. Depending on the hand position respective to the face, HBR was assessed in four different conditions: "hand-far," "hand-near" (eyes open), "side hand," and "hand-patched" (eyes closed). While sham and cathodal cerebellar stimulation had no significant effect, anodal tcDCS dramatically dampened the magnitude of the HBR, as measured by the area under the curve (AUC), in the "hand-patched" and "side hand" conditions only, for ipsilateral (F

Indexed as

BlinkingTranscranial Direct Current StimulationAdultCerebellumElectric StimulationFemaleHandHumansMaleMedian NerveMotor CortexPersonal SpaceYoung AdultCerebellar direct current stimulationcerebellumdefensive behaviorhand blink reflexperipersonal spacetDCS

Identifiers

PMID29845771
PMCPMC5974722
OpenAlexW2803496047

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.