Evidence map›Paper›PMID 29845764›Full record

Trial reportPhysiological reports2018

Unrestricted evening use of light-emitting tablet computers delays self-selected bedtime and disrupts circadian timing and alertness.

Evan D Chinoy, Jeanne F Duffy, Charles A Czeisler

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Melatonin-Measurement Methods and the Factors Modifying the Results. A Systematic Review of the Literature.International journal of environmental research and public health · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Evan D ChinoySleep Health Institute and Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts.
Jeanne F DuffySleep Health Institute and Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0003-4177-4179
Charles A CzeislerSleep Health Institute and Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, Massachusetts.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Sensitization of Human Circadian Responses to LightR01HL094654 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 2010 to 2013
$1.2M
NCATS NIH HHS UL1 TR001102NHLBI NIH HHS R01 HL094654NHLBI NIH HHS T32 HL007901
6 · The paper itself

Abstract

Consumer electronic devices play an important role in modern society. Technological advancements continually improve their utility and portability, making possible the near-constant use of electronic devices during waking hours. For most people, this includes the evening hours close to bedtime. Evening exposure to light-emitting (LE) devices can adversely affect circadian timing, sleep, and alertness, even when participants maintain a fixed 8-hour sleep episode in darkness and the duration of evening LE-device exposure is limited. Here, we tested the effects of evening LE-device use when participants were allowed to self-select their bedtimes, with wake times fixed as on work/school days. Nine healthy adults (3 women, 25.7 ± 3.0 years) participated in a randomized and counterbalanced study comparing five consecutive evenings of unrestricted LE-tablet computer use versus evenings reading from printed materials. On evenings when using LE-tablets, participants' self-selected bedtimes were on average half an hour later (22:03 ± 00:48 vs. 21:32 ± 00:27 h; P = 0.030), and they showed suppressed melatonin levels (54.17 ± 18.00 vs. 9.75 ± 22.75%; P < 0.001), delayed timing of melatonin secretion onset (20:23 ± 01:06 vs. 19:35 ± 00:59 h; P < 0.001), and later sleep onset (22:25 ± 00:54 vs. 21:54 ± 00:25 h; P = 0.041). When using LE-tablets, participants rated themselves as less sleepy in the evenings (P = 0.030) and less alert in the first hour after awakening on the following mornings (P < 0.001). These findings demonstrate that evening use of LE-tablets can induce delays in self-selected bedtimes, suppress melatonin secretion, and impair next-morning alertness, which may impact the health, performance, and safety of users.

Indexed as

Circadian RhythmComputers, HandheldSleepAdultBrainElectroencephalographyFemaleHumansLightMaleMelatoninWakefulnessYoung AdultMelatoninchronobiologymelatoninsleep

Identifiers

PMID29845764
PMCPMC5974725

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.