Evidence map›Paper›PMID 29845744›Full record

ArticleObesity (Silver Spring, Md.)2018

Fat-Free Mass and Skeletal Muscle Mass Five Years After Bariatric Surgery.

Lance E Davidson, Wen Yu, Bret H Goodpaster, James P DeLany, Elizabeth Widen, Thaisa Lemos, Gladys W Strain, Alfons Pomp, Anita P Courcoulas, Susan Lin and 3 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 4 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
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  12. Understanding Impact of Anti-Obesity Medications on Skeletal Muscle Mass Change Is Confounded by Measurement Methods.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Lance E DavidsonDepartment of Exercise Sciences, Brigham Young University, Provo, Utah, USA.ORCID 0000-0002-1383-0666
Wen YuDepartment of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York, USA.
Bret H GoodpasterTranslational Research Institute for Metabolism and Diabetes, Orlando, Florida, USA.
James P DeLanyDivision of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0366-3849
Elizabeth WidenDepartment of Nutritional Sciences, University of Texas at Austin, Austin, Texas.
Thaisa LemosDepartment of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York, USA.
Gladys W StrainGI Metabolic and Bariatric Surgery, Weill Cornell Medicine, New York, New York, USA.
Alfons PompGI Metabolic and Bariatric Surgery, Weill Cornell Medicine, New York, New York, USA.
Anita P CourcoulasGeneral Surgery, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Susan LinCenter for Family and Community Medicine, Columbia University Medical Center, New York, New York, USA.
Isaiah JanumalaDepartment of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York, USA.
John C ThorntonThornton Consulting, Mahopac, New York, USA.
Dympna GallagherDepartment of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York, USA.
Columbia University Irving Medical Center · USCornell University · USUniversity of Pittsburgh · USBrigham Young University · USThe University of Texas at Austin · USThornton Tomasetti (United States) · USTranslational Research Institute for Metabolism and Diabetes · US

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MARK D. HAYWARD · 2017 to 2026
$5.2M
Body Composition &REE Responses to Bariatric SurgeriesR01DK072507 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI GALLAGHER, DYMPNA · 2005 to 2015
$4.8M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
Pregnancy weight trajectories and offspring adiposityR00HD086304 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI WIDEN, ELIZABETH MARIE · 2018 to 2020
$744k
Interdisciplinary Training in Nutritional and Population Health SciencesT32DK091227 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUSSER, EZRA S., WOLGEMUTH, DEBRA J. · 2011 to 2015
$606k
Effects of Gastric Bypass Surgery and Sustained Weight Loss on Fracture RiskR21DK099619 · NIDDK · BRIGHAM YOUNG UNIVERSITY · PI DAVIDSON, LANCE ERIC · 2014 to 2015
$397k
Pregnancy weight trajectories and offspring adiposityK99HD086304 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI WIDEN, ELIZABETH MARIE · 2016 to 2017
$258k
NCATS NIH HHS UL1 TR000040NICHD NIH HHS K99 HD086304NICHD NIH HHS P2C HD042849NICHD NIH HHS R00 HD086304NIDDK NIH HHS P30 DK026687NIDDK NIH HHS R01 DK072507NIDDK NIH HHS R21 DK099619NIDDK NIH HHS T32 DK007559NIDDK NIH HHS T32 DK091227
6 · The paper itself

Abstract

objectiveThis study investigated changes in fat-free mass (FFM) and skeletal muscle 5 years after surgery in participants from the Longitudinal Assessment of Bariatric Surgery-2 trial.

methodsA three-compartment model assessed FFM, and whole-body magnetic resonance imaging (MRI) quantified skeletal muscle mass prior to surgery (T0) and 1 year (T1), 2 years (T2), and 5 years (T5) postoperatively in 93 patients (85% female; 68% Caucasian; age 44.2 ± 11.6 years) who underwent gastric bypass (RYGB), sleeve gastrectomy, or adjustable gastric band. Repeated-measures mixed models were used to analyze the data.

resultsSignificant weight loss occurred across all surgical groups in females from T0 to T1. FFM loss from T0 to T1 was greater after RYGB (mean ± SE: -6.9 ± 0.6 kg) than adjustable gastric band (-3.5 ± 1.4 kg; P < 0.05). Females with RYGB continued to lose FFM (-3.3 ± 0.7 kg; P < 0.001) from T1 to T5. A subset of males and females with RYGB and MRI-measured skeletal muscle showed similar initial FFM loss while maintaining FFM and skeletal muscle from T1 to T5.

conclusionsBetween 1 and 5 years following common bariatric procedures, FFM and skeletal muscle are maintained or decrease minimally. The changes observed in FFM and muscle during the follow-up phase may be consistent with aging.

Indexed as

AdiposityAdultBariatric SurgeryBiliopancreatic DiversionBody CompositionCohort StudiesFemaleGastrectomyGastric BypassHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedMuscle, SkeletalObesity, Morbid

Identifiers

PMID29845744
PMCPMC6014876
OpenAlexW2805149172

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.