ArticleMagnetic resonance in medicine2018
Chemical exchange saturation transfer fingerprinting for exchange rate quantification.
Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- An Interpretable Deep-Learning Approach for Efficient CEST Parameter Quantification: Importance-Ranked Saturation Transfer MRI Protocol.Magnetic resonance in medicine · 2026Article
- Optimization of Pulsed Saturation Transfer MR Fingerprinting (ST MRF) Acquisition Using the Cramér-Rao Bound and Sequential Quadratic Programming.Magnetic resonance in medicine · 2026Article
- Chemical exchange saturation transfer MRI for neurodegenerative diseases: An update on clinical and preclinical studies.Neural regeneration research · 2026Article
- Quantitative multi-metabolite imaging of Parkinson's disease using AI boosted molecular MRI.Npj imaging · 2025Article
- Quantitative molecular imaging using deep magnetic resonance fingerprinting.Nature protocols · 2025Review
- 3D multi-phase balanced non-steady-state free precession acquisition for multi-parameter mapping.Magma (New York, N.Y.) · 2025Article
- Article
- Induced saturation transfer recovery steady states (iSTRESS) for proton exchange rate mapping with CEST MRI, a preliminary study.Magnetic resonance imaging · 2024Article
- Validation of the presence of fast exchanging amine CEST effect at low saturation powers and its influence on the quantification of APT.Magnetic resonance in medicine · 2023Article
- Accelerated and quantitative three-dimensional molecular MRI using a generative adversarial network.Magnetic resonance in medicine · 2023Article
- Molecular MRI-Based Monitoring of Cancer Immunotherapy Treatment Response.International journal of molecular sciences · 2023Review
- Amide proton transfer imaging of Alzheimer's disease and Parkinson's disease.Magnetic resonance letters · 2023Review
- CEST MR fingerprinting (CEST-MRF) for brain tumor quantification using EPI readout and deep learning reconstruction.Magnetic resonance in medicine · 2023Article
- TowardBiosensors · 2022Review
- An end-to-end AI-based framework for automated discovery of rapid CEST/MT MRI acquisition protocols and molecular parameter quantification (AutoCEST).Magnetic resonance in medicine · 2022Article
- Learning-based optimization of acquisition schedule for magnetization transfer contrast MR fingerprinting.NMR in biomedicine · 2022Article
- Magnetic resonance fingerprinting: an overview.European journal of nuclear medicine and molecular imaging · 2021Review
- Review
- Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo.Current opinion in chemical biology · 2021Review
- Quantification of creatine kinase reaction rate in mouse hindlimb using phosphorus-31 magnetic resonance spectroscopic fingerprinting.NMR in biomedicine · 2021Article
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Authors and funding
7 authors.
Funding
Abstract
purposeThere is an increased interest to determine the exchange rate using CEST to provide pH information. However, current CEST quantification methods require lengthy scan times and do not address magnetization transfer effects. The purpose of this work was to apply the magnetic resonance fingerprinting (MRF) concept to CEST to achieve more efficient and accurate exchange rate quantification.
methodsThe proposed CEST fingerprinting method used varying saturation powers and saturation times to create unique signal evolutions for different exchange rates. The acquired signal was matched to a predefined dictionary to determine the exchange rate. The magnetization transfer effects were also addressed in the framework of CEST fingerprinting: The simulated dictionary could predict the signal curves without magnetization transfer effects, and comparing the dictionary to the acquired signals allowed the correction of the magnetization transfer effects. The CEST fingerprinting method was compared with the conventional pulsed quantitative CEST method using omega plots in the creatine phantom study.
resultsThe CEST fingerprinting method has a significantly reduced scan time (10 minutes versus 50 minutes) while providing more accurate exchange rate quantification using literature values as the reference.
conclusionIn this study, we demonstrate that CEST fingerprinting is more efficient (5 times faster) compared with pulsed quantitative CEST. It is also shown that the results of the proposed CEST fingerprinting technique are much closer to the literature values than pulsed quantitative CEST at 3 T.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.