Evidence map›Paper›PMID 29845583›Full record

ArticleAuto- immunity highlights2018

Anti-phospholipid IgG antibodies detected by line immunoassay differentiate patients with anti-phospholipid syndrome and other autoimmune diseases.

Cecilia Nalli, Valentina Somma, Laura Andreoli, Thomas Büttner, Peter Schierack, Michael Mahler, Dirk Roggenbuck, Angela Tincani

Open access · diamondAbstract read
In one paragraph

Article in Auto- immunity highlights, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Cecilia NalliUniversity of Brescia, Brescia, Italy.
Valentina SommaResearch and Development Department, Medipan GmbH, Dahlewitz, Berlin, Germany.
Laura AndreoliUniversity of Brescia, Brescia, Italy.
Thomas BüttnerResearch and Development Department, GA Generic Assays GmbH, Dahlewitz, Berlin, Germany.
Peter SchierackInstitute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968, Senftenberg, Germany.
Michael MahlerInova Diagnostics, San Diego, CA, USA.
Dirk RoggenbuckResearch and Development Department, Medipan GmbH, Dahlewitz, Berlin, Germany. dirk.roggenbuck@b-tu.de.ORCID http://orcid.org/0000-0002-6861-6827
Angela TincaniUniversity of Brescia, Brescia, Italy.
University of Brescia · ITMedipan (Germany) · DEBrandenburg University of Technology Cottbus-Senftenberg · DEGeneric Assays (Germany) · DENova Medical (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnti-phospholipid antibodies (aPL) analyzed by line immunoassay (LIA) can recognize beta

methodsThirty-four APS patients (14 arterial/venous thrombosis, 16 pregnancy morbidity, and 4 both), 41 patients with SARD lacking clinical APS criteria but demonstrating positivity for anti-β

resultsComparison of LIA with ELISA revealed a good agreement for the consensus criteria aPL aβ

conclusionsaD1/aD4-5 (ELISA) and aPG IgG (LIA) differentiate APS from SARD patients. PG appears to interact with β

Indexed as

Anti-phospholipid antibodyAnti-phospholipid syndromeBeta2 glycoprotein IDomain 1Phosphatidylglycerol

Identifiers

PMID29845583
PMCPMC5975024
OpenAlexW2807234612

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.