Evidence map›Paper›PMID 29845538›Full record

ReviewAdvances in experimental medicine and biology

Regulation and Function of NK and T Cells During Dengue Virus Infection and Vaccination.

Anuja Mathew

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anuja MathewDepartment of Cell and Molecular Biology, Institute for Immunology and Informatics, Providence, RI, USA. mathewa@uri.edu.

Funding

NK cell regulation of immune responses to dengueR21AI113479 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MATHEW, ANUJA · 2015 to 2016
$425k
NIAID NIH HHS R21 AI113479
6 · The paper itself

Abstract

The focus of this review is to discuss findings in the last 10 years that have advanced our understanding of human NK cell responses to dengue virus. We will review recently identified interactions of activating and inhibitory receptors on NK cells with dengue virus, human NK responses to natural dengue infection and highlight possible interactions by which NK cells may shape adaptive immune responses. T cell responses to natural dengue infection will be reviewed by Laura Rivino in Chap. 17 . With the advent of numerous dengue vaccine clinical trials, we will also review T and NK cell immune responses to dengue virus vaccination. As our understanding of the diverse functions of NK cell has advanced, it has become increasingly clear that human NK cell responses to viral infections are more complicated than initially recognized.

Indexed as

AnimalsDengueDengue VaccinesDengue VirusHumansKiller Cells, NaturalT-LymphocytesVaccinationDengue VaccinesActivationg receptors on NK cellsInhibitory receptors on NK cellsInnate immune systemKIR peptide-MHC interactionsT-cell response to dengue vaccine

Identifiers

PMID29845538
PMCPMC7121313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.