Evidence map›Paper›PMID 29844986›Full record

ArticlePeerJ2018

Selective constraint acting on TLR2 and TLR4 genes of Japanese

Quintin Lau, Takeshi Igawa, Tiffany A Kosch, Yoko Satta

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Quintin LauDepartment of Evolutionary Studies of Biosystems, Sokendai (Graduate University for Advanced Studies), Hayama, Kanagawa, Japan.
Takeshi IgawaAmphibian Research Center, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Tiffany A KoschOne Health Research Group, College of Public Health, Medical and Veterinary Sciences, James Cook University of North Queensland, Townsville, Queensland, Australia.
Yoko SattaDepartment of Evolutionary Studies of Biosystems, Sokendai (Graduate University for Advanced Studies), Hayama, Kanagawa, Japan.
The Graduate University for Advanced Studies, SOKENDAI · JPHiroshima University · JPJames Cook University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptors (TLRs) are an important component of innate immunity, the first line of pathogen defence. One of the major roles of TLRs includes recognition of pathogen-associated molecular patterns. Amphibians are currently facing population declines and even extinction due to chytridiomycosis caused by the

Indexed as

AmphibianRanidaeToll-like receptors

Identifiers

PMID29844986
PMCPMC5971840
OpenAlexW2804036441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.