Evidence map›Paper›PMID 29844906›Full record

ArticleMolecular and clinical oncology2018

Diagnostic and treatment hurdles in plasma cell myeloma with t(11;14) translocation: A case report.

Shun Yin Kong, Wing Kit Lam, Ka Shu Li, Ka Pik Yeung, Chung Yin Ha, Ho Kei Lai, Hay Nun Chan, Yiu Ming Yeung, Sze Fai Yip

Open access · diamondAbstract read
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In one paragraph

Article in Molecular and clinical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shun Yin KongDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Wing Kit LamDepartment of Pathology, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Ka Shu LiDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Ka Pik YeungDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Chung Yin HaDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Ho Kei LaiDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Hay Nun ChanDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Yiu Ming YeungDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Sze Fai YipDepartment of Medicine and Geriatrics, Tuen Mun Hospital, Hong Kong, SAR 999077, P.R. China.
Tuen Mun Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

t(11;14) translocation is one of the most common chromosomal abnormalities in plasma cell myeloma. The present case report presented a case of plasma cell myeloma with t(11;14) translocation, in which the plasma cells were small lymphoplasmacytoids in morphology with positive cluster of differentiation-20 and Cyclin D1 expression. These results led to initial diagnostic difficulties. The patient was refractory to bortezomib-based therapy, and responsive to vincristine, doxorubicin and dexamethasone. However, the prognostic value of t(11;14) in plasma cell myeloma remains to be determined. With recent advances in treatment options, physicians should be aware of the clinical and pathological characteristics of this translocation in plasma cell myeloma.

Indexed as

cluster of differentiation 20Cyclin D1plasma cell myelomat(11;14)

Identifiers

PMID29844906
PMCPMC5958828
OpenAlexW2801774455

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