Evidence map›Paper›PMID 29844820›Full record

ArticleOncology letters2018

A report of amelanotic malignant melanoma of the esophagus diagnosed appropriately with novel markers: A case report.

Junya Kobayashi, Daisuke Fujimoto, Makoto Murakami, Yasuo Hirono, Takanori Goi

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Unveiling a Rare Cause of Dysphagia.GE Portuguese journal of gastroenterology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Primary acral amelanotic melanoma: A rare case report.Molecular and clinical oncology · 2020
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Junya KobayashiDepartment of Surgery 1, Faculty of Medicine, University of Fukui, Fukui 910-1193, Japan.
Daisuke FujimotoDepartment of Surgery, Teikyo University Hospital, Kawasaki, Kanagawa 213-8507, Japan.
Makoto MurakamiDepartment of Surgery 1, Faculty of Medicine, University of Fukui, Fukui 910-1193, Japan.
Yasuo HironoDepartment of Surgery 1, Faculty of Medicine, University of Fukui, Fukui 910-1193, Japan.
Takanori GoiDepartment of Surgery 1, Faculty of Medicine, University of Fukui, Fukui 910-1193, Japan.
University of Fukui · JPTeikyo University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present case study reported of amelanotic malignant melanoma of the esophagus. A 68-year-old man underwent laparoscopic distal gastrectomy for early gastric cancer diagnosis. After gastrectomy, endoscopic examination revealed a protruded lesion lying adjacent to the melanosis area of the esophagus. Histology of the biopsy specimen suggested malignancy, but the diagnosis could not be made. The patient underwent trans-thoraco-abdominal curative subtotal esophagectomy. Immunohistochemical examination of the resected specimen was negative for HBM-45 and Melan-A. However, immunohistochemical examinations of SOX10 (Sry-related HMg-Box gene 10) and KBA.62, which are not associated with melanosome, were strongly positive, and tyrosinase was notably positive. A diagnosis primary of amelanotic malignant melanoma of the esophagus that consisted of only premelanosomes was made. The present findings suggest that, in the diagnosis of malignant melanoma, SOX10 and KBA.62 may be useful, particularly in diagnosing amelanotic malignant melanoma.

Indexed as

amelanotic malignant melanomaKBA.62melanosomeSOX10

Identifiers

PMID29844820
PMCPMC5958826
OpenAlexW2797858138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.