Evidence map›Paper›PMID 29844679›Full record

ArticleOncoTargets and therapy2018

5-Azacytidine treatment induces demethylation of

Xiaoli Ren, Huatao Li, Xianyi Song, Yuhong Wu, Yun Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Genetic and epigenetic landscape of OExploration of targeted anti-tumor therapy · 2025
    Review
  3. Review
  4. Epigenetic alterations in canine mammary cancer.Genetics and molecular biology · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. International journal of molecular sciences · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xiaoli RenHeilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Huatao LiDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Xianyi SongHeilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yuhong WuHeilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yun LiuHeilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Northeast Agricultural University · CNQingdao Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCanine mammary gland tumors (CMGTs) are the most common, spontaneous types of neoplasias in female dogs. Aberrant MATERIALS AND

methodsThe effects of 5-azacytidine on CHMm and CHMp cell proliferation were evaluated by MTT assay. The

results5-Azacytidine may suppress the proliferation of CHMm and CHMp cells. Furthermore, the

conclusionThese results suggest that

Indexed as

5-azacytidinecanine mammary gland tumorCHMmCHMpDAPK1DNA methylationMGMT

Identifiers

PMID29844679
PMCPMC5961471
OpenAlexW2800992408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.