Evidence map›Paper›PMID 29844677›Full record

ReviewInternational journal of tryptophan research : IJTR2018

The Influence of Nicotinamide on Health and Disease in the Central Nervous System.

Rosemary A Fricker, Emma L Green, Stuart I Jenkins, Síle M Griffin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of tryptophan research : IJTR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 1 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 1 synthesis or guideline pooled it, 196 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  16. Article
  17. Nicotinamide Prevents the Plasticity Impairments and the Cognitive Dysfunction Caused by Bone Fracture in Older Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  18. Review
  19. Review
  20. Review

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rosemary A FrickerSchool of Medicine and Institute for Science and Technology in Medicine, Keele University, Staffordshire, UK.
Emma L GreenSchool of Medicine and Institute for Science and Technology in Medicine, Keele University, Staffordshire, UK.
Stuart I JenkinsSchool of Medicine and Institute for Science and Technology in Medicine, Keele University, Staffordshire, UK.
Síle M GriffinSchool of Medicine and Institute for Science and Technology in Medicine, Keele University, Staffordshire, UK.
Keele University · GB

Funding

Parkinson's UK G-0911
6 · The paper itself

Abstract

Nicotinamide, the amide form of vitamin B

Indexed as

Alzheimer’s diseaseHuntington’s diseasemitochondrianeurodegenerationneuronal deathneuroprotectionniacinNicotinamideParkinson’s diseasevitamin B3

Identifiers

PMID29844677
PMCPMC5966847
OpenAlexW2804555851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.