Evidence map›Paper›PMID 29844667›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2018

Distribution and characteristics of COPD phenotypes - results from the Polish sub-cohort of the POPE study.

Aleksander Kania, Rafał Krenke, Krzysztof Kuziemski, Małgorzata Czajkowska-Malinowska, Natalia Celejewska-Wójcik, Barbara Kuźnar-Kamińska, Małgorzata Farnik, Juliusz Bokiej, Marta Miszczuk, Iwona Damps-Konstańska and 5 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Article
  13. Impact of symptom variability on clinical outcomes in COPD: analysis of a longitudinal cohort.International journal of chronic obstructive pulmonary disease · 2019
    Article
  14. CAT Score and SGRQ Definitions of Chronic Bronchitis as an Alternative to the Classical Definition.International journal of chronic obstructive pulmonary disease · 2019
    Article
  15. Article
  16. Characteristics of COPD Phenotypes in Serbia.International journal of chronic obstructive pulmonary disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aleksander KaniaDepartment of Pulmonology, II Chair of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.
Rafał KrenkeDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland.
Krzysztof KuziemskiDepartment of Allergology and Pneumonology, Medical University of Gdańsk, Gdańsk, Poland.
Małgorzata Czajkowska-MalinowskaDepartment of Lung Diseases and Respiratory Failure, Regional Center of Pulmonology, Bydgoszcz, Poland.
Natalia Celejewska-WójcikDepartment of Pulmonology, II Chair of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.
Barbara Kuźnar-KamińskaDepartment of Pulmonology, Allergology and Respiratory Oncology, Poznań University of Medical Sciences, Poznań, Poland.
Małgorzata FarnikDepartment of Pneumology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Juliusz BokiejDepartment of Lung Diseases, Regional Hospital Center Jelenia Góra, Jelenia Góra, Poland.
Marta MiszczukDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland.
Iwona Damps-KonstańskaDepartment of Allergology and Pneumonology, Medical University of Gdańsk, Gdańsk, Poland.
Marcin GrabickiDepartment of Pulmonology, Allergology and Respiratory Oncology, Poznań University of Medical Sciences, Poznań, Poland.
Marzena Trzaska-SobczakDepartment of Pneumology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Krzysztof SładekDepartment of Pulmonology, II Chair of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.
Halina Batura-GabryelDepartment of Pulmonology, Allergology and Respiratory Oncology, Poznań University of Medical Sciences, Poznań, Poland.
Adam BarczykDepartment of Pneumology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to examine the distribution of predefined phenotypes, demographic data, clinical outcomes, and treatment of patients who were included in the Polish cohort of the Phenotypes of COPD in Central and Eastern Europe (POPE) study. Patients and methods: This was a sub-analysis of the data from the Polish cohort of the POPE study, an international, multicenter, observational cross-sectional survey of COPD patients in Central and Eastern European countries. The study included patients aged >40 years, with a confirmed diagnosis of COPD, and absence of exacerbation for at least 4 weeks before study inclusion. A total of seven Polish centers participated in the study. Results: Among the 430 Polish COPD patients enrolled in the study, 61.6% were non-exacerbators (NON-AE), 25.3% were frequent exacerbators with chronic bronchitis (AE CB), 7.9% were frequent exacerbators without chronic bronchitis (AE NON-CB), and 5.1% met the definition of asthma-COPD overlap syndrome (ACOS). There were statistically significant differences among these phenotypes in terms of symptom load, lung function, comorbidities, and treatment. Patients with the AE CB phenotype were most symptomatic with worse lung function, and more frequently reported anxiety and depression. Patients with the ACOS phenotype were significantly younger and were diagnosed with COPD earlier than those with other COPD phenotypes; those with the ACOS phenotype were also more often atopic and obese. Conclusion: There is significant heterogeneity among COPD patients in the Polish population in terms of phenotype and clinical outcome. The non-exacerbator phenotype is observed most frequently in Poland, while the frequent exacerbator with chronic bronchitis phenotype is the most symptomatic.

Indexed as

AdultAgedAged, 80 and overAge of OnsetAnxietyAsthmaBronchitis, ChronicComorbidityCross-Sectional StudiesDepressionFemaleHealth SurveysHumansLungMaleMiddle Agedasthma-COPD overlap syndromechronic obstructive pulmonary diseasephenotypes

Identifiers

PMID29844667
PMCPMC5963485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.