Evidence map›Paper›PMID 29844643›Full record

ArticleActa Cardiologica Sinica2018

Anti-Inflammatory Effect of Gallic Acid-Eluting Stent in a Porcine Coronary Restenosis Model.

Kyung Seob Lim, Jun-Kyu Park, Myung Ho Jeong, In Ho Bae, Dae Sung Park, Jae Won Shim, Jung Ha Kim, Hyun Kuk Kim, Sung Soo Kim, Doo Sun Sim and 3 more

Abstract read
In one paragraph

Article in Acta Cardiologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
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  8. ChronicActa Cardiologica Sinica · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Kyung Seob LimKorea Cardiovascular Stent Institute, Jangsung.
Jun-Kyu ParkCGBio. Co. Ltd, Jangseong-gun.
Myung Ho JeongKorea Cardiovascular Stent Institute, Jangsung.
In Ho BaeKorea Cardiovascular Stent Institute, Jangsung.
Dae Sung ParkKorea Cardiovascular Stent Institute, Jangsung.
Jae Won ShimKorea Cardiovascular Stent Institute, Jangsung.
Jung Ha KimKorea Cardiovascular Stent Institute, Jangsung.
Hyun Kuk KimDivision of Cardiology, Chosun University Hospital, Gwangju, Korea.
Sung Soo KimDivision of Cardiology, Chosun University Hospital, Gwangju, Korea.
Doo Sun SimCardiovascular Convergence Research Center, Nominated by the Korea Ministry of Health and Welfare.
Young Joon HongCardiovascular Convergence Research Center, Nominated by the Korea Ministry of Health and Welfare.
Ju Han KimCardiovascular Convergence Research Center, Nominated by the Korea Ministry of Health and Welfare.
Youngkeun AhnCardiovascular Convergence Research Center, Nominated by the Korea Ministry of Health and Welfare.
Chosun University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGallic acid (3,4,5-trihydroxybenzoic acid) is a natural polyphenol and strong natural antioxidant found abundantly in red wine and green tea. The aim of this study was to examine the anti-inflammatory effect of a novel gallic acid-eluting stent in a porcine coronary restenosis model.

methodsFifteen pigs were randomized into three groups; in which a total of 30 coronary arteries (10 in each group) were implanted with gallic acid-eluting stents (GESs, n = 10), gallic acid and sirolimus-eluting stents (GSESs, n = 10), or sirolimus-eluting stents (SESs, n = 10). Histopathologic analysis was performed 28 days after stenting.

resultsThere were no significant differences in injury score and fibrin score among the groups, however there were significant differences in the internal elastic lamina (4.0 ± 0.83 mm

conclusionsThe GES group had a greater percent area of stenosis than the SES group. Although gallic acid in the GES and GSES groups did not show a synergistic effect in suppressing neointimal hyperplasia, it resulted in greater inhibition of the inflammatory reaction in the porcine coronary restenosis model than in the SES group.

Indexed as

InflammationPercutaneous coronary interventionRestenosisStent

Identifiers

PMID29844643
PMCPMC5968338
OpenAlexW2990279743

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.