ArticleActa Cardiologica Sinica2018
In-Hospital Implementation of Evidence-Based Medications is Associated with Improved Survival in Diabetic Patients with Acute Coronary Syndrome - Data from TSOC ACS-DM Registry.
Article in Acta Cardiologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- A Narrative Review and Expert Panel Recommendations on Dyslipidaemia Management After Acute Coronary Syndrome in Countries Outside Western Europe and North America.Advances in therapy · 2020Pooled it
- TAMIS Consensus on Multidisciplinary Team Care in Post-Acute Stage of Acute Coronary Syndrome: Nutrition, Pharmacotherapy, and Cardiac Rehabilitation.Acta Cardiologica Sinica · 2026Article
- Effects of preexisting and new-onset diabetes mellitus on clinical outcomes of patients with heart failure.Annals of medicine · 2025Article
- Ticagrelor Versus Clopidogrel in Patients with Acute Coronary Syndrome and Chronic Kidney Disease: A Real-World Analysis from a National Registry.Medicina (Kaunas, Lithuania) · 2025Article
- Rationale and Study Design of the TSOC-Fully Organized Registry for the Management of Symptomatic ACS Study (T-FORMOSA Study).Acta Cardiologica Sinica · 2023Article
- Clinical Feasibility of Biofunctionalized Magnetic Nanoparticles for Detecting Multiple Cardiac Biomarkers in Emergency Chest Pain Patients.Acta Cardiologica Sinica · 2020Article
- Predictive Power of In-Hospital and Long-Term Mortality of the GRACE, TIMI, Revised CADILLAC and PAMI Score in NSTEMI Patients with Diabetes - Data from TSOC ACS-DM Registry.Acta Cardiologica Sinica · 2020Article
- 2020 Focused Update of the 2012 Guidelines of the Taiwan Society of Cardiology for the Management of ST-Segment Elevation Myocardial Infarction.Acta Cardiologica Sinica · 2020Review
- Impact of Acute Kidney Injury and Baseline Renal Impairment on Prognosis Among Patients Undergoing Percutaneous Coronary Intervention.Acta Cardiologica Sinica · 2020Article
- The Use and Clinical Outcomes of Single-Burr Rotational Atherectomy: The Experience of a Local Hospital in Taiwan.Acta Cardiologica Sinica · 2020Article
- Article
- Considering ISCHEMIA in the Context of FAME and FAME 2: A Call for the Universal Adoption of Invasive Ischemia-Guided Coronary Intervention Approach in Chronic Coronary Syndrome.Acta Cardiologica Sinica · 2020Article
- Article
- An Ideal Vascular Access in a Patient with Acute Coronary Syndrome and Cardiogenic Shock: The Arterial Cannula of Veno-Arterial Extracorporeal Membrane Oxygenation.Acta Cardiologica Sinica · 2019Article
- A Bridge Still Too Far.Acta Cardiologica Sinica · 2019Article
- Acute Myocardial Infarction Involving Left Main Artery in a Patient with Antiphospholipid Syndrome.Acta Cardiologica Sinica · 2019Article
- Comparative Effectiveness and Safety of Antithrombotic Therapy in Atrial Fibrillation Patients Presenting with Acute Coronary Syndrome or Percutaneous Coronary Intervention.Acta Cardiologica Sinica · 2019Article
- Early Phase II Comprehensive Cardiac Rehabilitation after Acute Myocardial Infarction.Acta Cardiologica Sinica · 2019Article
- Appropriate Use of Dual Antiplatelet Therapy.Acta Cardiologica Sinica · 2019Article
- Impact of Pharmacist Interventions on the Long-Term Clinical Outcomes in Patients with Myocardial Infarction.Acta Cardiologica Sinica · 2019Article
Corrections and comments
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Authors and funding
28 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with acute coronary syndrome (ACS) and diabetes mellitus (DM) receive less aggressive treatment and have worse outcomes in Taiwan. We sought to explore whether the current practices of prescribing guideline-directed medical therapy (GDMT) for ACS and clinical outcomes have improved over time.
methodsA total of 1534 consecutive diabetic patients with ACS were enrolled between 2013 and 2015 from 27 hospitals in the nationwide registry initiated by the Taiwan Society of Cardiology (the TSOC ACS-DM Registry). Baseline and clinical demographics, treatment, and clinical outcomes were compared to those of 1000 ACS patients with DM recruited in the Taiwan ACS-full spectrum (ACS-FS) Registry, which was performed between 2008 and 2010.
resultsCompared to the DM patients in the Taiwan ACS-FS Registry, even though reperfusion therapy was carried out in significantly fewer patients, the primary percutaneous coronary intervention (PCI) rate for ST-segment elevation myocardial infarction (STEMI) and the prescription rates of GDMT for ACS including P2Y12 inhibitors, renin-angiotensin blockers, beta-blockers, and statins were significantly higher in those in the TSOC ACS-DM Registry. Moreover, significant reductions in 1-year mortality, recurrent nonfatal MI and stroke were observed compared to those of the DM patients in the Taiwan ACS-FS Registry. Multivariate analysis identified reperfusion therapy in combination with GDMT as a strong predictor of better 1-year outcomes [hazard ratio (95% confidence interval) = 0.54 (0.33-0.89)].
conclusionsMarked improvements in performing primary PCI for STEMI and prescribing GDMT for ACS were observed over time in Taiwan. This was associated with improved 1-year event-free survival in the diabetic patients with ACS.
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