Evidence map›Paper›PMID 29844641›Full record

ReviewActa Cardiologica Sinica2018

2018 Expert Consensus on the Management of Adverse Effects of Antiplatelet Therapy for Acute Coronary Syndrome in Taiwan.

Yi-Heng Li, Chih-Yuan Fang, I-Chang Hsieh, Wei-Chun Huang, Tsung-Hsien Lin, Shih-Hsien Sung, Chiung-Zuan Chiu, Chiung-Jen Wu, Kou-Gi Shyu, Po-Yuan Chang and 9 more

Abstract readReview
In one paragraph

Review in Acta Cardiologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. A Brave New World.Acta Cardiologica Sinica · 2019
    Article
  9. Appropriate Use of Dual Antiplatelet Therapy.Acta Cardiologica Sinica · 2019
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Yi-Heng LiDivision of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital and College of Medicine, Tainan.
Chih-Yuan FangDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung.
I-Chang HsiehDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan.
Wei-Chun HuangDivision of Cardiology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung and School of Medicine, National Yang Ming University, Taipei.
Tsung-Hsien LinDivision of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung.
Shih-Hsien SungDepartment of Medicine, Taipei Veterans General Hospital and National Yang Ming University, Taipei.
Chiung-Zuan ChiuDivision of Cardiology, Shin-Kong Wu Ho Su Memorial Hospital, Taipei, and School of Medicine, Fu Jen Catholic University, New Taipei City.
Chiung-Jen WuDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung.
Kou-Gi ShyuDivision of Cardiology, Shin-Kong Wu Ho Su Memorial Hospital, Taipei, and School of Medicine, Fu Jen Catholic University, New Taipei City.
Po-Yuan ChangCardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei.
Ching-Chang FangDivision of Cardiology, Department of Internal Medicine, Tainan Municipal Hospital, Tainan.
Tse-Min LuDepartment of Medicine, Taipei Veterans General Hospital and National Yang Ming University, Taipei.
Ching-Pei ChenDepartment of Cardiology, Changhua Christian Hospital, Changhua.
Wei-Chen TaiDivision of Hepato-gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital.
Chau-Chyun SheuDivision of Pulmonary and Critical Care Medicine, Kaohsiung Medical University Hospital.
Kai-Che WeiDepartment of Dermatology, Kaohsiung Veterans General Hospital, Kaohsiung.
Yi-Hsiu HuangDepartment of Urology, Taipei Veterans General Hospital.
Hsing-Mei WuDepartment of Otolaryngology, Shin-Kong Wu Ho Su Memorial Hospital, Taipei.
Juey-Jen Hwang HwangCardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei.
Kaohsiung Chang Gung Memorial Hospital · TWKaohsiung Medical University · TWKaohsiung Veterans General Hospital · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiplatelet therapy is a key component in the treatment of acute coronary syndrome (ACS). The management of ACS has evolved considerably over recent years with the development of new and more potent antiplatelet agents. Clinical trials on ACS have demonstrated that potent antiplatelet agents can more effectively reduce cardiovascular events. However, there is a tipping point between safety and efficacy, beyond which the risk of bleeding and other adverse effects can outweigh the benefits of antiplatelet therapy. Striking a balance between safety and efficacy remains a major challenge. A consensus meeting of an expert panel composed of Taiwanese experts was held to provide recommendations for the management of adverse effects in patients with ACS receiving antiplatelet therapy. The common adverse effects of antiplatelet therapy include upper gastrointestinal bleeding, ecchymosis, hematuria, epistaxis and ticagrelor-related dyspnea. In this study, a literature review of these adverse events was performed and recommendations for the management were made.

Indexed as

Acute coronary syndromeAntiplatelet therapyExpert consensusGuidance

Identifiers

PMID29844641
PMCPMC5968336
OpenAlexW2887425146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.