Evidence map›Paper›PMID 29844517›Full record

ArticleScientific reports2018

Beta and gamma human papillomaviruses in anal and genital sites among men: prevalence and determinants.

Vitaly Smelov, Richard Muwonge, Olga Sokolova, Sandrine McKay-Chopin, Carina Eklund, Boris Komyakov, Tarik Gheit

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
  6. Viruses · 2023
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  7. Article
  8. Article
  9. Review
  10. Article
  11. The Prevalence of High Carcinogenic Risk of HPV Genotypes among HIV-Positive and HIV-Negative MSM from Russia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Vitaly SmelovPrevention and Implementation Group, International Agency for Research on Cancer, World Health Organization, Lyon, France. smelovv@iarc.fr.ORCID 0000-0002-7353-1561
Richard MuwongeScreening Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Olga SokolovaFaculty of Medicine, St. Petersburg State University, St. Petersburg, Russia.
Sandrine McKay-ChopinInfections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Carina EklundDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Boris KomyakovDepartment of Urology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.
Tarik GheitInfections and Cancer Biology Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Centre international de recherche sur le cancer · FRKarolinska Institutet · SENorth-Western State Medical University named after I.I. Mechnikov · RUSt Petersburg University · RU

Funding

World Health Organization 001
6 · The paper itself

Abstract

Data regarding the anogenital distribution of and type-specific concordance for cutaneous β- and γ-HPV types in men who have sex with women is limited and geographically narrow. Knowledge of determinants of anogenital detection of cutaneous HPV types in different regions is needed for better understanding of the natural history and transmission dynamics of HPV, and its potential role in the development of anogenital diseases. Genital and anal canal samples obtained from 554 Russian men were screened for 43 β-HPVs and 29 γ-HPVs, using a multiplex PCR combined with Luminex technology. Both β- and γ-HPVs were more prevalent in the anal (22.8% and 14.1%) samples than in the genital (16.8% and 12.3%) samples. Low overall and type-specific concordance for β-HPVs (3.5% and 1.1%) and γ-HPVs (1.3% and 0.6%) were observed between genital and anal samples. HIV-positive men had higher anal β- (crude OR = 12.2, 95% CI: 5.3-28.1) and γ-HPV (crude OR = 7.2, 95% CI: 3.3-15.4) prevalence than HIV-negative men. Due to the lack of genital samples from the HIV-positive men, no comparison was possible for HIV status in genital samples. The lack of type-specific positive concordance between genital and anal sites for cutaneous β- and γ-HPV types in heterosexual men posits the needs for further studies on transmission routes to discriminate between contamination and true HPV infection. HIV-positive status may favor the anal acquisition or modify the natural history of cutaneous HPV types.

Indexed as

AdolescentAdultAnal CanalBetapapillomavirusCoinfectionGammapapillomavirusGenitalia, MaleGenotypeHeterosexualityHIV-1HIV InfectionsHumansMaleMiddle AgedPapillomavirus InfectionsPrevalence

Identifiers

PMID29844517
PMCPMC5974254
OpenAlexW2805850190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.