Evidence map›Paper›PMID 29844501›Full record

ArticleScientific reports2018

Possible Obesogenic Effects of Bisphenols Accumulation in the Human Brain.

Pantelis Charisiadis, Xanthi D Andrianou, Thomas P van der Meer, Wilfred F A den Dunnen, Dick F Swaab, Bruce H R Wolffenbuttel, Konstantinos C Makris, Jana V van Vliet-Ostaptchouk

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Endocrine disruptors, obesity, and metabolic syndrome.Turkish journal of medical sciences · 2025
    Review
  9. Dietary bisphenols exposure as an influencing factor of body mass index.Environmental health : a global access science source · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Are BPA Substitutes as Obesogenic as BPA?International journal of molecular sciences · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Pantelis CharisiadisCyprus International Institute for Environmental and Public Health, Cyprus University of Technology, Limassol, 3041, Cyprus.ORCID 0000-0001-7260-192X
Xanthi D AndrianouCyprus International Institute for Environmental and Public Health, Cyprus University of Technology, Limassol, 3041, Cyprus.
Thomas P van der MeerDepartment of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Wilfred F A den DunnenDepartment of Pathology & Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Dick F SwaabNetherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.
Bruce H R WolffenbuttelDepartment of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Konstantinos C MakrisCyprus International Institute for Environmental and Public Health, Cyprus University of Technology, Limassol, 3041, Cyprus. konstantinos.makris@cut.ac.cy.
Jana V van Vliet-OstaptchoukDepartment of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. j.v.van.vliet@umcg.nl.ORCID 0000-0002-7943-3153
University Medical Center Groningen · NLCyprus University of Technology · CYNetherlands Institute for Neuroscience · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence of bisphenols' obesogenic effects on humans is mixed and inconsistent. We aimed to explore the presence of bisphenol A (BPA), bisphenol F (BPF) and chlorinated BPA (ClBPA), collectively called the bisphenols, in different brain regions and their association with obesity using post-mortem hypothalamic and white matter brain material from twelve pairs of obese (body mass index (BMI) >30 kg/m

Indexed as

Adipose TissueBenzhydryl CompoundsBisphenol A CompoundsBisphenol F CompoundsBody Mass IndexBrainChlorophenolsEndocrine DisruptorsEnvironmental ExposureEnvironmental PollutantsHalogenationHumansHypothalamusObesityPhenolsWhite MatterBenzhydryl Compoundsbisphenol ABisphenol A Compoundsbisphenol FBisphenol F CompoundsChlorophenolsEndocrine DisruptorsEnvironmental PollutantsPhenols

Identifiers

PMID29844501
PMCPMC5974368
OpenAlexW2807690497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.