ArticleScientific reports2018
Sub-threshold signal encoding in coupled FitzHugh-Nagumo neurons.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Parameter estimation of the network of FitzHugh-Nagumo neurons based on the speed-gradient and filtering.Journal of computational neuroscience · 2025Article
- Spectral resonance in Fitzhugh-Nagumo neuron system: relation with stochastic resonance and its role in EMG signal characterization.Cognitive neurodynamics · 2024Article
- Noise-induced synchrony of two-neuron motifs with asymmetric noise and uneven coupling.Frontiers in computational neuroscience · 2024Article
- Neuronal Transmission of Subthreshold Periodic Stimuli Via Symbolic Spike Patterns.Entropy (Basel, Switzerland) · 2020Article
- Decreased electrocortical temporal complexity distinguishes sleep from wakefulness.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite intensive research, the mechanisms underlying the neural code remain poorly understood. Recent work has focused on the response of a single neuron to a weak, sub-threshold periodic signal. By simulating the stochastic FitzHugh-Nagumo (FHN) model and then using a symbolic method to analyze the firing activity, preferred and infrequent spike patterns (defined by the relative timing of the spikes) were detected, whose probabilities encode information about the signal. As not individual neurons but neuronal populations are responsible for sensory coding and information transfer, a relevant question is how a second neuron, which does not perceive the signal, affects the detection and the encoding of the signal, done by the first neuron. Through simulations of two stochastic FHN neurons we show that the encoding of a sub-threshold signal in symbolic spike patterns is a plausible mechanism. The neuron that perceives the signal fires a spike train that, despite having an almost random temporal structure, has preferred and infrequent patterns which carry information about the signal. Our findings could be relevant for sensory systems composed by two noisy neurons, when only one detects a weak external input.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.