Evidence map›Paper›PMID 29844195›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Yoshikatsu Hosoda, Munemitsu Yoshikawa, Masahiro Miyake, Yasuharu Tabara, Jeeyun Ahn, Se Joon Woo, Shigeru Honda, Yoichi Sakurada, Chieko Shiragami, Hideo Nakanishi and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 113 citations in OpenAlex.

  1. Guideline
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  7. Associations ofOphthalmology science · 2026
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 3 countries.

Yoshikatsu HosodaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Munemitsu YoshikawaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Masahiro MiyakeDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Yasuharu TabaraCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, 6068503 Kyoto, Japan.
Jeeyun AhnDepartment of Ophthalmology, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, 07061 Seoul, Korea.
Se Joon WooDepartment of Ophthalmology, Seoul National University Bundang Hospital, College of Medicine Kyeonggi, Seoul National University, 13620 Seoul, Korea.
Shigeru HondaDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 6500017 Kobe, Japan.
Yoichi SakuradaDepartment of Ophthalmology, University of Yamanashi, 4008510 Yamanashi, Japan.
Chieko ShiragamiDepartment of Ophthalmology, Kagawa University, 7610793 Kagawa, Japan.
Hideo NakanishiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Akio OishiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Sotaro OotoDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Akiko MikiDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 6500017 Kobe, Japan.
Nagahama Study Group
Tomohiro IidaDepartment of Ophthalmology, Tokyo Womens' Medical University, 1628666 Tokyo, Japan.
Hiroyuki IijimaDepartment of Ophthalmology, University of Yamanashi, 4008510 Yamanashi, Japan.
Makoto NakamuraDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 6500017 Kobe, Japan.
Chiea Chuen KhorSingapore National Eye Centre, Singapore Eye Research Institute, 168751 Singapore.
Tien Yin WongSingapore National Eye Centre, Singapore Eye Research Institute, 168751 Singapore.
Kyuyoung SongDepartment of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, 138736 Seoul, Korea.
Kyu Hyung ParkDepartment of Ophthalmology, Seoul National University Bundang Hospital, College of Medicine Kyeonggi, Seoul National University, 13620 Seoul, Korea.
Ryo YamadaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, 6068503 Kyoto, Japan.
Fumihiko MatsudaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, 6068503 Kyoto, Japan.
Akitaka TsujikawaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan.
Kenji YamashiroDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 6068507 Kyoto, Japan; yamashro@kuhp.kyoto-u.ac.jp.ORCID 0000-0001-9354-8558
Kyoto University · JPKobe University · JPTokyo Women's Medical University · JPUlsan College · KRKagawa University · JPNational University of Singapore · SGSeoul National University · KRSeoul National University Bundang Hospital · KRSingapore National Eye Center · SGUniversity of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central serous chorioretinopathy (CSC) is a common disease affecting younger people and may lead to vision loss. CSC shares phenotypic overlap with age-related macular degeneration (AMD). As recent studies have revealed a characteristic increase of choroidal thickness in CSC, we conducted a genome-wide association study on choroidal thickness in 3,418 individuals followed by TaqMan assays in 2,692 subjects, and we identified two susceptibility loci:

Indexed as

AllelesCase-Control StudiesCentral Serous ChorioretinopathyChoroidComplement Factor HGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMacular DegenerationMiddle AgedPolymorphism, Single NucleotideReceptors, Vasoactive Intestinal Peptide, Type IIComplement Factor HReceptors, Vasoactive Intestinal Peptide, Type IIcentral serous chorioretinopathyCFHchoroidal thicknessGWASVIPR2

Identifiers

PMID29844195
PMCPMC6004488
OpenAlexW2805485714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.