A novel high-affinity inhibitor against the human ATP-sensitive Kir6.2 channel.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

1. Inhibition Mechanism of Pancreatic KResearch (Washington, D.C.) · 2026
   Article
2. Venom Peptides, Polyphenols and Alkaloids: Are They the Next Antidiabetics That Will Preserve β-Cell Mass and Function in Type 2 Diabetes?Cells · 2023
   Review
3. Personalized Therapeutics for KAnnual review of pharmacology and toxicology · 2023
   Review
4. Mechanistic insights on KATP channel regulation from cryo-EM structures.The Journal of general physiology · 2023
   Review
5. Kir6.1 and SUR2B in Cantú syndrome.American journal of physiology. Cell physiology · 2022
   Review
6. Blocking Kir6.2 channels with SpTx1 potentiates glucose-stimulated insulin secretion from murine pancreatic β cells and lowers blood glucose in diabetic mice.eLife · 2022
   Article
7. Development of IFrontiers in pharmacology · 2021
   Article
8. Kir Channel Molecular Physiology, Pharmacology, and Therapeutic Implications.Handbook of experimental pharmacology · 2021
   Review
9. Peptide Toxins Targeting KV Channels.Handbook of experimental pharmacology · 2021
   Review
10. A family of orthologous proteins from centipede venoms inhibit the hKir6.2 channel.Scientific reports · 2019
    Article
11. Insulin Release Mechanism Modulated by Toxins Isolated from Animal Venoms: From Basic Research to Drug Development Prospects.Molecules (Basel, Switzerland) · 2019
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors at 1 institution in 1 country.

Funding

Abstract

Indexed as