Evidence map›Paper›PMID 29844133›Full record

ArticleGenetics2018

Loss of Elongation-Like Factor 1 Spontaneously Induces Diverse, RNase H-Related Suppressor Mutations in

Bahjat F Marayati, Alena L Drayton, James F Tucker, Reid H Huckabee, Alicia M Anderson, James B Pease, Clifford W Zeyl, Ke Zhang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bahjat F MarayatiDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
Alena L DraytonDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
James F TuckerDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
Reid H HuckabeeDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
Alicia M AndersonDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
James B PeaseDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
Clifford W ZeylDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101.
Ke ZhangDepartment of Biology, Center for Molecular Communication and Signaling, Wake Forest University, Winston-Salem, North Carolina 27101 Zhangk@wfu.edu.ORCID 0000-0003-1973-0874
Wake Forest University · US

Funding

Determination of a Novel Epigenetic Silencing MechanismR15GM119105 · NIGMS · WAKE FOREST UNIVERSITY · PI REID, KE ZHANG · 2016 to 2016
$420k
NIGMS NIH HHS R15 GM119105
6 · The paper itself

Abstract

A healthy individual may carry a detrimental genetic trait that is masked by another genetic mutation. Such suppressive genetic interactions, in which a mutant allele either partially or completely restores the fitness defect of a particular mutant, tend to occur between genes that have a confined functional connection. Here we investigate a self-recovery phenotype in

Indexed as

Gene DeletionMutationATP-Binding Cassette TransportersCell NucleusGenome, FungalGenomic InstabilityPhenotypeRibonuclease HRNA, FungalSchizosaccharomycesSchizosaccharomyces pombe ProteinsWhole Genome SequencingATP-Binding Cassette TransportersElf1 protein, S pombeRibonuclease HRNA, FungalSchizosaccharomyces pombe Proteinselongation-like factor 1 (Elf1)genome stabilityRNA nuclear accumulationRNase Hsuppressor

Identifiers

PMID29844133
PMCPMC6063228
OpenAlexW2806583811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.