Evidence map›Paper›PMID 29844049›Full record

ArticleAntimicrobial agents and chemotherapy2018

Analysis of the Tunicamycin Biosynthetic Gene Cluster of Streptomyces chartreusis Reveals New Insights into Tunicamycin Production and Immunity.

David Widdick, Sylvain F Royer, Hua Wang, Natalia M Vior, Juan Pablo Gomez-Escribano, Benjamin G Davis, Mervyn J Bibb

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  6. Review
  7. Tunicamycin: chemical synthesis and biosynthesis.The Journal of antibiotics · 2019
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

David WiddickDepartment of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Sylvain F RoyerDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Hua WangDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Natalia M ViorDepartment of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Juan Pablo Gomez-EscribanoDepartment of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Benjamin G DavisDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Mervyn J BibbDepartment of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, United Kingdom mervyn.bibb@jic.ac.uk.
University of Oxford · GBJohn Innes Centre · GBNorwich Research Park · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J004561/1Biotechnology and Biological Sciences Research Council BB/J006637/1Biotechnology and Biological Sciences Research Council BB/J009725/1
6 · The paper itself

Abstract

The tunicamycin biosynthetic gene cluster of

Indexed as

Gene Expression Regulation, BacterialGenes, BacterialMultigene FamilyAnti-Bacterial AgentsATP-Binding Cassette TransportersBase SequenceGene DeletionGenetic Complementation TestMethyltransferasesOperonPromoter Regions, GeneticStreptomycesStreptomyces coelicolorTunicamycinAnti-Bacterial AgentsATP-Binding Cassette TransportersMethyltransferasesTunicamycinantibioticbiosynthesisimmunityStreptomycestunicamycin

Identifiers

PMID29844049
PMCPMC6105854
OpenAlexW2807505034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.