ArticleTrends in microbiology2018
Surface Area to Volume Ratio: A Natural Variable for Bacterial Morphogenesis.
Article in Trends in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed.
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- Mapping life's disparity and evolutionary constraints in a geometric complexity space.Science advances · 2026Article
- Evaluating the scientific and regulatory case for the deployment of the radioresistant genusFrontiers in microbiology · 2026Review
- Maintenance of cytoplasmic and membrane densities shapes cellular geometry in Escherichia coli.Nature communications · 2025Article
- Pear-Shaped Eggs Evolved to Maximize the Surface Area-to-Volume Ratio, Increase Metabolism, and Shorten Incubation Time in Birds.Integrative zoology · 2025Article
- Modeling reveals a metabolic basis of competition amongmSystems · 2025Article
- Mechanics ofMolecular biology of the cell · 2025Article
- Uropathogenic Escherichia coli proliferate as a coccoid morphotype inside human host cells.PLoS biology · 2025Article
- Cell Geometry and Membrane Protein Crowding Constrain Growth Rate, Overflow Metabolism, Respiration, and Maintenance Energy.bioRxiv : the preprint server for biology · 2025Article
- The geometry of life: testing the scaling of whole-organism surface area and volume using sharks.Royal Society open science · 2025Article
- Intracellular diffusion in the cytoplasm increases with cell size in fission yeast.Molecular biology of the cell · 2025Article
- Microplastic Passage through the Fish and Crayfish Digestive Tract Alters Particle Surface Properties.Environmental science & technology · 2025Article
- Coupling Artificial Intelligence with Proper Mathematical Algorithms to Gain Deeper Insights into the Biology of Birds' Eggs.Animals : an open access journal from MDPI · 2025Article
- The proteome is a terminal electron acceptor.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Terrestrial-aquatic connectivity structures microbial communities during the formation of thermokarst lakes.ISME communications · 2025Article
- Accurate calculation of the content volume, density and original weight of museum curated eggs.Scientific reports · 2024Article
- Carbapenem-ResistantNanomaterials (Basel, Switzerland) · 2024Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
An immediately observable feature of bacteria is that cell size and shape are remarkably constant and characteristic for a given species in a particular condition, but vary quantitatively with physiological parameters such as growth rate, indicating both genetic and environmental regulation. However, despite decades of research, the molecular mechanisms underlying bacterial morphogenesis have remained incompletely characterized. We recently demonstrated that a wide range of bacterial species exhibit a robust surface area to volume ratio (SA/V) homeostasis. Because cell size, shape, and SA/V are mathematically interconnected, if SA/V is indeed the natural variable that cells actively monitor, this finding has critical implications for our understanding of bacterial morphogenesis, placing fundamental constraints on the sizes and shapes that cells can adopt. In this Opinion article we discuss the broad implications that this novel perspective has for the field of bacterial growth and morphogenesis.
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Registered trials
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