Evidence map›Paper›PMID 29843825›Full record

ArticleEpidemiology and infection2018

Association of influenza outbreaks with advanced pediatric medical support.

Jennifer Guyther, Richard Lichenstein, Yonghong Gao, James A Zhou, Adebola Ajao, Priti K Bajaj, Veronica A Combs, James C King

Abstract read
In one paragraph

Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Severe Illnesses Associated With Outbreaks of Respiratory Syncytial Virus and Influenza in Adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer GuytherDepartments of Emergency Medicine and Pediatrics,University of Maryland School of Medicine,Baltimore, Maryland,USA.
Richard LichensteinDepartment of Pediatrics,University of Maryland School of Medicine,Baltimore, Maryland,USA.
Yonghong GaoUS Department of Health and Human Services,Biomedical Advanced Research and Development Authority,Washington DC,USA.
James A ZhouUS Department of Health and Human Services,Biomedical Advanced Research and Development Authority,Washington DC,USA.
Adebola AjaoUS Food and Drug Administration,Silver Spring, Maryland,USA.
Priti K BajajDepartment of Pediatrics,University of Maryland School of Medicine,Baltimore, Maryland,USA.
Veronica A CombsDepartment of Pediatrics,University of Maryland School of Medicine,Baltimore, Maryland,USA.
James C KingUS Department of Health and Human Services,Biomedical Advanced Research and Development Authority,Washington DC,USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrospective data evaluated increases in advanced medical support for children with medically attended acute respiratory illness (MAARI) during influenza outbreak periods (IOP). Advanced support included hospitalisation, intensive care unit admission, or mechanical ventilation, for children aged 0-17 years hospitalised in Maryland's 50 acute-care hospitals over 12 influenza seasons. Weekly numbers of positive influenza tests in the Maryland area defined IOP for each season as the fewest consecutive weeks, including the peak week containing at least 85% of positive tests with a 2-week buffer on either side of the IOP. Peak IOP (PIOP) was defined as four consecutive weeks containing the peak week with the most number of positive influenza tests. Off-PIOP was defined as the 'shoulder' weeks during each IOP. Non-influenza season (NIS) was the remaining weeks of that study season. Rate ratios of mean daily MAARI-related admissions resulting in advanced medical support outcomes during PIOP or Off-PIOP were compared with the NIS and were significantly elevated for all 12 study seasons combined. The results suggest that influenza outbreaks are associated with increased advanced medical support utilisation by children with MAARI. We feel that this data may help preparedness for severe influenza epidemics or pandemic.

Indexed as

Acute DiseaseAdolescentChildChild, PreschoolDisease OutbreaksFemaleHospitalizationHumansInfantInfluenza, HumanIntensive Care Units, PediatricMaleMarylandPoisson DistributionRespiration, ArtificialRespiratory Tract DiseasesAdvanced medical supporthospitalisationinfluenzaintensive care unitmechanical ventilation

Identifiers

PMID29843825
PMCPMC9133675

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.