ArticleLipids in health and disease2018
Triglyceride to high-density lipoprotein cholesterol (HDL-C) ratio and arterial stiffness in Japanese population: a secondary analysis based on a cross-sectional study.
Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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42 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Dose-response associations of triglyceride to high-density lipoprotein cholesterol ratio and triglyceride-glucose index with arterial stiffness risk.Lipids in health and disease · 2024Pooled it
- Association between sleep duration and chronic lung diseases among Chinese middle-aged and older adults: A cross-sectional study.PloS one · 2026Article
- The gamma-glutamyltransferase-to-estimated glomerular filtration rate composite index is associated with arterial stiffness: a cross-sectional secondary analysis of a health check-up population.Frontiers in endocrinology · 2026Article
- Pulse Wave Velocity Progression Determinants: No Significant Association with Novel Lipids Parameter.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- The association between volume reduction ratio and time after ultrasound-guided microwave ablation for benign thyroid nodules of different compositions.Quantitative imaging in medicine and surgery · 2025Article
- The relationship between blood glucose and clinical outcomes after extracorporeal circulation: a retrospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Multiple metals exposure and estimated pulse wave velocity: a cross-sectional analysis of the US adults.Frontiers in public health · 2025Article
- Non-linear associations of a body shape index with diabetes among adults: A cross-sectional study.PloS one · 2025Article
- The relationship between triglyceride to high-density lipoprotein cholesterol ratio and cardiovascular high risk: a cross-sectional investigation.Frontiers in endocrinology · 2025Article
- Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study.Lipids in health and disease · 2024Article
- Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study.Scientific reports · 2024Article
- Defining the threshold: triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio's non-linear impact on tubular atrophy in primary membranous nephropathy.Frontiers in endocrinology · 2024Article
- Associations between blood manganese levels and sarcopenia in adults: insights from the National Health and Nutrition Examination Survey.Frontiers in public health · 2024Article
- Threshold effect of atherogenic index of plasma on type 2 diabetes mellitus and modification by uric acid in normal-weight adults with hypertension.Frontiers in endocrinology · 2024Article
- Inverted U-shaped relationship between serum vitamin B12 and α-Klotho levels in US adults: a cross-sectional study.Frontiers in nutrition · 2024Article
- Triglycerides/HDL cholesterol ratio and type 2 diabetes incidence: Panasonic Cohort Study 10.Cardiovascular diabetology · 2023Article
- Association between Triglyceride-Glucose Index and carotid plaque in Japanese population: a cross-sectional study.BMJ open · 2023Article
- Ultrasound-guided microwave ablation for benign thyroid nodules results in earlier and faster nodule shrinkage in patients with Hashimoto's thyroiditis than in those with normal thyroid function.Frontiers in surgery · 2023Article
- Association between the metabolic score for insulin resistance (METS-IR) and arterial stiffness among health check-up population in Japan: a retrospective cross-sectional study.Frontiers in endocrinology · 2023Article
- Associations of non-HDL-C and triglyceride/HDL-C ratio with coronary plaque burden and plaque characteristics in young adults.Bosnian journal of basic medical sciences · 2022Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
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Abstract
backgroundPrevious studies have revealed that triglyceride to high-density lipoprotein cholesterol (HDL-C) ratio (henceforth TG/HDL-C) is one of major risk factors of cardiovascular diseases, insulin resistance and metabolism syndrome. However, there are fewer scientific dissertations about the correlation between TG/HDL-C and bapWV. This study was undertaken to investigate the relationship between Triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio and brachial-ankle pulse wave velocity (baPWV) in Japanese.
methodsThe present study was a cross-sectional study. 912 Japanese men and women, aging 24-84 years old, received a health medical a health check-up program including the results from baPWV inspection and various standardized questionnaire in a health examination Center in Japan. Main outcome measures included TG/HDL-C ratio, baPWV, fatty liver, postmenopausal status. Abdominal ultrasonography was used to diagnose fatty liver. Postmenopausal state was defined as beginning 1 year after the cessation of menses. It was noted that the entire study was completed by Fukuda et al., and uploaded the data to the DATADRYAD website. The author only used this data for secondary analysis.
resultsAfter adjusting potential confounders (age, sex, BMI, SBP, DBP, AST, ALT, GGT, uric acid, fasting glucose, TC, LDL, eGFR, smoking and exercise status, fatty liver, alcohol consumption and ABI), non-linear relationship was detected between TG/HDL-C and baPWV, whose point was 5.6. The effect sizes and the confidence intervals on the left and right sides of inflection point were 12.7 (1.9 to 23.5) and - 16.7 (- 36.8 to 3.3), respectively. Subgroup analysis showed, in participants with excessive alcohol consumption (more than 280 g/week), that TG/HDL-C had a negative correlation with BAPWV (β = - 30.7, 95%CI (- 53.1, - 8.4)), and the P for interaction was less than 0.05,
conclusionThe relationship between TG/HDL-C and baPWV is non-linear. TG/HDL-C was positively related with baPWV when TG/HDL-C is less than 5.6. In addition, while the trend is opposite in excessive alcoholic subjects.
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