ArticleVirology journal2018
Torque teno virus dynamics during the first year of life.
Article in Virology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Torque Teno Virus (TTV) Plasma Load and Immune Reconstitution Post-Transplantation in Patients with Lymphoproliferative Disorders: A Systematic Review.Pathogens (Basel, Switzerland) · 2026Pooled it
- Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review.European journal of clinical investigation · 2025Pooled it
- Torque Teno Virus (TTV) Plasma Load and Immune Reconstitution in People Living with HIV: A Systematic Review.Microorganisms · 2026Review
- Anelloviruses: From General Biology to Their Role as Biomarkers of Immune Competence in HIV Infection.Viruses · 2026Review
- Infant gut anellovirus composition associates with early life factors and childhood atopic disease.Nature communications · 2025Article
- Anellovirus constraint from 2 to 6 months postpartum followed by betatorquevirus and gammatorquevirus dominance in serum and milk.Journal of virology · 2025Article
- Anellovirus species in the serum of acute febrile patients from Mato Grosso, central Western Brazil, 2019.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Study on the Molecular Prevalence and Genotypic Distribution of Torque Teno Virus in Iranian Hemodialysis Patients.BioMed research international · 2025Article
- Torque teno virus: a potential marker of immune reconstitution in youths with vertically acquired HIV.Scientific reports · 2024Observational
- Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand.Viruses · 2024Article
- Article
- SCANellome: Analysis of the Genomic Diversity of Human and Non-Human Primate Anelloviruses from Metagenomics Data.Viruses · 2023Article
- Transfusion transmitted virus and dengue virus among healthy blood donors: A prevalence report from Jordan.Biomolecules & biomedicine · 2023Article
- The Human Virome and Its Crosslink with Glomerulonephritis and IgA Nephropathy.International journal of molecular sciences · 2023Review
- Understanding torquetenovirus (TTV) as an immune marker.Frontiers in medicine · 2023Review
- Maternal plasma and salivary anelloviruses in pregnancy and preterm birth.Frontiers in medicine · 2023Article
- Phylogenetic analysis of torque teno virus in Romania: possible evidence of distinct geographical distribution.Archives of virology · 2022Article
- Article
- Article
- Diversity and Long-Term Dynamics of Human Blood Anelloviruses.Journal of virology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTorque teno virus is a small chronically persisting circular negative ssDNA virus reaching near 100% prevalence. It is reported to be a marker for immune function in immunocompromised patients. The possibility of vertical maternal-fetal transmission remains controversial but incidence rate of TTV DNA in children increased with age. TTV dynamics well studied for allogeneic hematopoietic stem cell transplantation as a predictor of post-transplant complications but there is no viral proliferation kinetics data for other patient groups or healthy individuals. The aim of this study was to determine TTV dynamics during the first year of life of healthy infants.
methodsNinety eight clinically healthy breastfeeding infants (1-12 months of age) were analyzed by quantitative PCR for the whole blood TTV load with the test sensitivity of about 1000 viral copies per milliliter of blood (total number of samples including repeatedly tested infants was 109).
results67% of all analyzed samples were TTV-positive demonstrating significant positive correlation between age and TTV load (r = 0.81, p < 0.01).
conclusionsThis is the first study to suggest that viral load increases during the first year of life reaching a plateau after 6 months with strong proliferation for the first 60 days. Our data well correlates with TTV dynamics in patients following allogeneic hematopoietic stem cell transplantation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.