Evidence map›Paper›PMID 29843700›Full record

ArticleBMC endocrine disorders2018

Comparison of health-related quality of Life (HRQOL) among patients with pre-diabetes, diabetes and normal glucose tolerance, using the 15D-HRQOL questionnaire in Greece: the DEPLAN study.

Konstantinos Makrilakis, Stavros Liatis, Afroditi Tsiakou, Chryssoula Stathi, Eleftheria Papachristoforou, Despoina Perrea, Nicholas Katsilambros, Nikolaos Kontodimopoulos, Dimitrios Niakas

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Article in BMC endocrine disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  8. Glycemic status and health-related quality of life (HRQOL) in populations at risk of diabetes in two Latin American cities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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  9. Article
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  11. Variables associated with poor health-related quality of life among patients with dyslipidemia in Jordan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Konstantinos MakrilakisFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece. kmakrila@med.uoa.gr.ORCID http://orcid.org/0000-0002-4160-0577
Stavros LiatisFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece.
Afroditi TsiakouFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece.
Chryssoula StathiFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece.
Eleftheria PapachristoforouFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece.
Despoina PerreaLaboratory for Experimental Surgery and Surgical Research "Christeas Hall", University of Athens Medical School, Athens, Greece.
Nicholas KatsilambrosFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece.
Nikolaos KontodimopoulosHellenic Open University, Patras, Greece.
Dimitrios NiakasFirst Department of Propaedeutic Medicine, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, 17 Ag. Thoma St, 11527, Athens, Greece.

Funding

Commission of the European Communities, Directorate C - Public Health 2004310
6 · The paper itself

Abstract

backgroundDiabetes mellitus is usually preceded by a pre-diabetic stage before the clinical presentation of the disease, the influence of which on persons' quality of life is not adequately elucidated. The purpose of this study was to compare the Health-Related Quality of Life (HRQOL) of persons with pre-diabetes with that of diabetes or normal glucose tolerance (NGT), using the validated HRQOL-15D questionnaire.

methodsThe HRQOL-15D scores of 172 people with pre-diabetes (108 with Impaired Fasting Glucose [IFG], 64 with Impaired Glucose Tolerance [IGT], aged 58.3 ± 10.3 years) and 198 with NGT (aged 54.4 ± 10.1 years) from the Greek part of the DEPLAN study (Diabetes in Europe - Prevention using Lifestyle, Physical Activity and Nutritional Intervention), were compared to 100 diabetes patients' scores (aged 60.9 ± 12.5 years, diabetes duration 17.0 ± 10.0 years, HbA1c 7.2 ± 1.2%), derived from the outpatient Diabetes Clinic of a University Hospital.

resultsThe diabetes patients' HRQOL-15D score (0.8605) was significantly lower than the pre-diabetes' (0.9008) and the controls' (0.9092) (p < 0.001). There were no differences in the total score between the controls and the group with pre-diabetes. However, examination of individual parameters of the score showed that people with IGT had lower scores compared to the control group, as related to the parameters of "mobility" and "psychological distress". No differences were found in any component of the HRQOL-15D score between the control group and the IFG group, nor between the two groups with pre-diabetes (IFG vs. IGT).

conclusionsPersons with pre-diabetes had a similar HRQOL score with healthy individuals, and a higher score than persons with diabetes. Specific components of the score, however, were lower in the IGT group compared to the controls. These findings help clarify the issue of HRQOL of persons with pre-diabetes and its possible impact on prevention.

Indexed as

Quality of LifeCase-Control StudiesCross-Sectional StudiesDiabetes MellitusFemaleFollow-Up StudiesGlucoseGlucose IntoleranceGreeceHumansMaleMiddle AgedPrediabetic StatePrognosisSurveys and QuestionnairesGlucoseDiabetes mellitusHRQOL-15D questionnairePre-diabetesQuality of life

Identifiers

PMID29843700
PMCPMC5975583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.