SynthesisBMC psychiatry2018
Associations between loneliness and perceived social support and outcomes of mental health problems: a systematic review.
Synthesis in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 622 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
622 citing papers in PubMed, 12 syntheses or guidelines pooled it.
- Longitudinal associations between loneliness and outcomes of Common Mental Disorders (CMDs): A systematic review and meta-analysis.BMC medicine · 2026Pooled it
- Systematic Review of Loneliness and Social Isolation Interventions in Obesity and Obesity-Related Complications.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Effects of Psychosocial Interventions on Loneliness Amongst Long-Term Care Residents: A Systematic Review and Meta-Analysis.Journal of advanced nursing · 2026Pooled it
- Linking mental health and digital addiction in general population: an overview of thematic evolution and trends from a science mapping perspective.Frontiers in psychiatry · 2026Pooled it
- Psychosocial and economic factors related to better health among older adults in Europe - a systematic review.Frontiers in public health · 2026Pooled it
- Examining the mediating roles of self-esteem and social support in the link between digital addiction and mental health: findings from a meta-analytic structural equation modeling study.Frontiers in public health · 2026Pooled it
- Pooled it
- Functioning, disability, and health of individuals with Hikikomori (prolonged social withdrawal) and their families: A systematic review and meta-analysis of case-control studies.The International journal of social psychiatry · 2025Pooled it
- Prevalence of metabolic syndrome and its association with selected factors among people with psychiatric conditions in Ethiopia: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- The medial prefrontal cortex as a proposed regulatory structure in the relationship between anxiety and perceived social support: a review.BMC psychology · 2025Pooled it
- The relationship between social support and mental health in athletes: a systematic review and meta-analysis.Frontiers in psychology · 2025Pooled it
- Navigating the biopsychosocial landscape: A systematic review on the association between social support and chronic pain.PloS one · 2025Pooled it
- A Randomized Sham-Controlled Trial of Heart Rate Variability Biofeedback Following Traumatic Brain Injury (TBI).Applied psychophysiology and biofeedback · 2026Trial
- Incentivizing social support in the randomized mobile Lifestyle Intervention for Food and Exercise study: the impact of gamification on social support perceptions, provision, and receipt.Translational behavioral medicine · 2026Trial
- A randomised feasibility trial comparing group and individual format GROUPS FOR HEALTH interventions for loneliness in people who experience psychosis.Psychology and psychotherapy · 2025Trial
- The impact of craft creation practice on university students' mental health: a moderated network analysis.Frontiers in public health · 2025Trial
- Social contact recovery and depressive symptoms after the pandemic lockdowns: the lasting impact of child neglect.European journal of psychotraumatology · 2026Article
- Loneliness and Personality: Noise- and Bias-Free True Correlations Between Loneliness and the Big Five Personality Domains.Journal of personality · 2026Article
- What makes a lonely child: environmental, health, and multimodal neuroimaging correlates of prospective loneliness in the ABCD study.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Envisioning a Hopeful Future Despite Schizophrenia: The Role of Self-Concept Clarity and Narrative Identity.Scandinavian journal of psychology · 2026Article
562 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe adverse effects of loneliness and of poor perceived social support on physical health and mortality are established, but no systematic synthesis is available of their relationship with the outcomes of mental health problems over time. In this systematic review, we aim to examine the evidence on whether loneliness and closely related concepts predict poor outcomes among adults with mental health problems.
methodsWe searched six databases and reference lists for longitudinal quantitative studies that examined the relationship between baseline measures of loneliness and poor perceived social support and outcomes at follow up. Thirty-four eligible papers were retrieved. Due to heterogeneity among included studies in clinical populations, predictor measures and outcomes, a narrative synthesis was conducted.
resultsWe found substantial evidence from prospective studies that people with depression who perceive their social support as poorer have worse outcomes in terms of symptoms, recovery and social functioning. Loneliness has been investigated much less than perceived social support, but there is some evidence that greater loneliness predicts poorer depression outcome. There is also some preliminary evidence of associations between perceived social support and outcomes in schizophrenia, bipolar disorder and anxiety disorders.
conclusionsLoneliness and quality of social support in depression are potential targets for development and testing of interventions, while for other conditions further evidence is needed regarding relationships with outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.