Evidence map›Paper›PMID 29843627›Full record

Trial reportBMC pregnancy and childbirth2018

Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial.

Sumaya Huque, Ian Roberts, Bukola Fawole, Rizwana Chaudhri, Sabaratnam Arulkumaran, Haleema Shakur-Still

2 registry-linked trialsOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05070689 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Placenta Accreta Spectrum Disorders: A. Chohan Continuous Squeezing Suture (ACCSS) for Controlling Haemorrahge From Lower Uterine Segment at Caesarean Section

TypeinterventionalSponsorSharif Medical Research CenterRan2021 to 2022Enrolled20ConditionsPlacenta AccretaArmsACCSS
NCT06353074 completednot on this mapstarted 2021, after this paper: background citation

Uterine Preservation With Acar's Atony Suture for Postpartum Uterine Atony

TypeobservationalSponsorNecmettin Erbakan UniversityRan2021 to 2023Enrolled16ConditionsUterine Atony With Hemorrhage, Postpartum Hemorrhage
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.

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  17. Bakri Balloon for Treatment of Postpartum Hemorrhage: A Real-World 2016-2020 Study in 279 Women from a Single Center.Medical science monitor : international medical journal of experimental and clinical research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Sumaya HuqueClinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Ian RobertsClinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Ian.roberts@lshtm.ac.uk.ORCID http://orcid.org/0000-0003-1596-6054
Bukola FawoleDepartment of Obstetrics and Gynaecology, National Institute of Maternal and Child Health, College of Medicine, University of Ibadan, Orita-Mefa, Ibadan, Nigeria.
Rizwana ChaudhriDepartment of Obstetrics and Gynaecology, Rawalpindi Medical University, Rawalpindi, Pakistan.
Sabaratnam ArulkumaranSt George's University, Cranmer Terrace, London, SW17 0RE, UK.
Haleema Shakur-StillClinical Trials Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
University of London · GBRawalpindi Medical University · PKSt George's, University of London · GBUniversity of Ibadan · NG

Funding

Bill and Melinda Gates Foundation OPP1095618Department of Health HICF-T2-0510-007Wellcome TrustWellcome Trust WT094947
6 · The paper itself

Abstract

backgroundPeripartum hysterectomy can cause significant morbidity and mortality. Most studies of peripartum hysterectomy are from high income countries. This cohort study examined risk factors for peripartum hysterectomy using data from Africa, Asia, Europe and the Americas.

methodsWe used data from the World Maternal Antifibrinolytic (WOMAN) trial carried out in 193 hospitals in 21 countries. Peripartum hysterectomy was defined as hysterectomy within 6 weeks of delivery as a complication of postpartum haemorrhage. Univariable and multivariable random effects logistic regression models were used to analyse risk factors. A hierarchical conceptual framework guided our multivariable analysis.

resultsFive percent of women had a hysterectomy (1020/20,017). Haemorrhage from placenta praevia/accreta carried a higher risk of hysterectomy (17%) than surgical trauma/tears (5%) and uterine atony (3%). The adjusted odds ratio (AOR) for hysterectomy in women with placenta praevia/accreta was 3.2 (95% CI: 2.7-3.8), compared to uterine atony. The risk of hysterectomy increased with maternal age. Caesarean section was associated with fourfold higher odds of hysterectomy than vaginal delivery (AOR 4.3, 95% CI: 3.6-5.0). Mothers in Asia had a higher hysterectomy incidence (7%) than mothers in Africa (5%) (AOR: 1.2, 95% CI: 0.9-1.7).

conclusionsPlacenta praevia/accreta is associated with a higher risk of peripartum hysterectomy. Other risk factors for hysterectomy are advanced maternal age, caesarean section and giving birth in Asia.

Indexed as

AdultAfricaAsiaCesarean SectionCohort StudiesDelivery, ObstetricEuropeFemaleHumansHysterectomyIncidenceOdds RatioPeripartum PeriodPlacenta AccretaPlacenta PreviaPostpartum HemorrhageAfricaAsiaCaesarean sectionConceptual frameworkPeripartum hysterectomyPlacenta accretaPostpartum haemorrhage

Identifiers

PMID29843627
PMCPMC5975404
OpenAlexW2807145756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.