Evidence map›Paper›PMID 29843426›Full record

ReviewBrain sciences2018

Neuromodulatory Treatments for Alcohol Use Disorder: A Review.

Anne-Mary N Salib, Allen L Ho, Eric S Sussman, Arjun V Pendharkar, Casey H Halpern

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. The Inferior Colliculus in Alcoholism and Beyond.Frontiers in systems neuroscience · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anne-Mary N SalibDepartment of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Bldg./R-227, Stanford, CA 94305, USA. asalib.ucsandiego@gmail.com.
Allen L HoDepartment of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Bldg./R-227, Stanford, CA 94305, USA. allenlho@gmail.com.
Eric S SussmanDepartment of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Bldg./R-227, Stanford, CA 94305, USA. esussman@stanford.edu.
Arjun V PendharkarDepartment of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Bldg./R-227, Stanford, CA 94305, USA. apendhar@stanford.edu.
Casey H HalpernDepartment of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Bldg./R-227, Stanford, CA 94305, USA. chalpern@stanford.edu.
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) is a prevalent condition characterized by chronic alcohol-seeking behaviors and has become a significant economic burden with global ramifications on public health. While numerous treatment options are available for AUD, many are unable to sustain long-term sobriety. The nucleus accumbens (NAcc) upholds an integral role in mediating reward behavior and has been implicated as a potential target for deep brain stimulation (DBS) in the context of AUD. DBS is empirically thought to disrupt pathological neuronal synchrony, a hallmark of binge behavior. Pre-clinical animal models and pilot human clinical studies utilizing DBS for the treatment of AUD have shown promise for reducing alcohol-related cravings and prolonging abstinence. In this review, we outline the various interventions available for AUD, and the translational potential DBS has to modulate functionality of the NAcc as a treatment for AUD.

Indexed as

alcoholismbinge drinkingdeep brain stimulationmouse modelsneuromodulationnucleus accumbens

Identifiers

PMID29843426
PMCPMC6025548
OpenAlexW2804475259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.