Evidence map›Paper›PMID 29843384›Full record

ReviewInternational journal of environmental research and public health2018

Alcoholism: A Multi-Systemic Cellular Insult to Organs.

Ucee Dguzeh, Natasha C Haddad, Kathia T S Smith, John O Johnson, Angelia A Doye, Judith K Gwathmey, Georges E Haddad

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Short-Term Alcohol Consumption Is Sufficient to Disrupt Microbial Communities and the Intestinal and Circulating Metabolites in a Non-Human Primate Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Alcohol-Induced Blood-Brain Barrier Impairment: An In Vitro Study.International journal of environmental research and public health · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ucee DguzehDepartment of Physiology, New Jersey Medical School Rutgers, 185 S Orange Ave, Newark, NJ 07103, USA. Uceedguzeh@gmail.com.
Natasha C HaddadDepartment of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA. nmc.haddad@gmail.com.
Kathia T S SmithDepartment of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA. kathia.smith@howard.edu.
John O JohnsonDepartment of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA. jjohnson@howard.edu.
Angelia A DoyeGwathmey Inc., Cambridge, MA 02138, USA. adoye@gwathmey.com.
Judith K GwathmeyGwathmey Inc., Cambridge, MA 02138, USA. jgwathmey@gwathmey.com.
Georges E HaddadDepartment of Physiology and Biophysics, College of Medicine, Howard University, 520 W Street, NW, #2309, Washington, DC 20059, USA. haddadgeorge@msn.com.ORCID 0000-0003-3664-9875
Howard University · USBoston University · USRutgers, The State University of New Jersey · US

Funding

STRUCTURAL/FUNCTIONAL CHARACTERIZATION OF AMINOGLYCOSIDEG12RR003048 · NCRR · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 1985 to 2011
$19.0M
MECHANISMS OF ALCOHOL-INDUCED CARDIOMYOPATHY.R15AA019816 · NIAAA · HOWARD UNIVERSITY · PI HADDAD, GEORGES E. · 2011 to 2011
$442k
NCRR NIH HHS G12 RR003048NIAAA NIH HHS R15 AA019816
6 · The paper itself

Abstract

Alcohol abuse can affect more than the heart and the liver. Many observers often do not appreciate the complex and differing aspects of alcohol's effects in pathophysiologies that have been reported in multiple organs. Chronic alcohol abuse is known to be associated with pathophysiological changes that often result in life-threatening clinical outcomes, e.g., breast and colon cancer, pancreatic disease, cirrhosis of the liver, diabetes, osteoporosis, arthritis, kidney disease, immune system dysfunction, hypertension, coronary artery disease, cardiomyopathy, and can be as far-reaching as to cause central nervous system disorders. In this review article, we will discuss the various organs impacted by alcohol abuse. The lack of clear guidelines on the amount and frequency of alcohol intake, complicated by personal demographics, make extrapolations to real-life practices at best difficult for public health policy-makers.

Indexed as

AlcoholismCell Physiological PhenomenaHumansalcohol abusealcohol beneficial effectsmulti-organ effects of alcohol

Identifiers

PMID29843384
PMCPMC6028910
OpenAlexW2803422601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.