ArticleFoods (Basel, Switzerland)2018
Protective Effect of Selenium-Enriched Ricegrass Juice against Cadmium-Induced Toxicity and DNA Damage in HEK293 Kidney Cells.
Article in Foods (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Natural Defenses Against Cadmium Toxicity: Mechanisms and Emerging Strategies - A Review.Biological trace element research · 2026Review
- Antioxidative and anti-cytogenotoxic potential ofHeliyon · 2024Article
- Antioxidant and genoprotective effects of osthole against cadmium-induced DNA damage: anResearch in pharmaceutical sciences · 2022Article
- Antagonism of cadmium-induced liver injury in ducks by α-bisabolol.Frontiers in veterinary science · 2022Article
- Identifying Chemical Composition, Safety and Bioactivity of Thai Rice Grass Extract Drink in Cells and Animals.Molecules (Basel, Switzerland) · 2021Article
- Content of total aflatoxin, lead, and cadmium in the bovine meat and edible offal: study of their human dietary intake, health risk assessment, and molecular biomarkers.Environmental science and pollution research international · 2021Article
- Estimation of cadmium content in Egyptian foodstuffs: health risk assessment, biological responses of human HepG2 cells to food-relevant concentrations of cadmium, and protection trials using rosmarinic and ascorbic acids.Environmental science and pollution research international · 2019Article
- Functional and Bioactive Properties of Food: The Challenges Ahead.Foods (Basel, Switzerland) · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium (Cd) contamination in food is a problem endangering human health. Cd detoxication is an interesting topic particularly using food which provides no side effects. Ricegrass juice is a squeezed juice from young rice leaves which is introduced as a functional drink rich in polyphenol components. Se-enrichment into ricegrass is initiated to provide extra advantages of their functional properties. The protective role of ricegrass juice (RG) and Se-enriched ricegrass juice (Se-RG) against Cd toxicity during pre-, co- and post-treatment on HEK293 kidney cells were investigated. Results confirmed that RG and Se-RG had very low toxicity for kidney cells. Both extracts showed a protective role during pre-treatment and co-treatment against Cd toxicity by exerting a reduction in malondialdehyde (MDA) content and the percentage of DNA damage in tail and tail length of the comets over the Cd-treated cells. However, the Se-RG indicated additional benefits in all properties over RG. High Se content in Se-RG resulted in more protective effects of the regular ricegrass juice. In summary, this study provides clear evidence that Se-enriched ricegrass juice has potential to be developed as a functional food to protect the human body from Cd contamination via the reduction of oxidative stress and DNA damage.
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