ArticleCancer biomarkers : section A of Disease markers2018
Reduced mean platelet volume is associated with poor prognosis in esophageal cancer.
Article in Cancer biomarkers : section A of Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic and clinicopathological significance of pretreatment mean platelet volume in cancer: a meta-analysis.BMJ open · 2020Pooled it
- A prognostic nomogram that includes MPV in esophageal squamous cell carcinoma.Cancer medicine · 2023Article
- Adjuvant chemotherapy for lymph node positive esophageal squamous cell cancer: The prediction role of low mean platelet volume.Frontiers in oncology · 2022Article
- Utility of Blood Markers for Predicting Outcomes of Fertility Preservation in Patients With Breast Cancer.Frontiers in endocrinology · 2022Article
- The clinical significance of preoperative serum fibrinogen levels and platelet counts in patients with gallbladder carcinoma.BMC gastroenterology · 2021Article
- Economical and easily detectable markers of digestive tumors: platelet parameters.Biomarkers in medicine · 2021Article
- Platelets: The Emerging Clinical Diagnostics and Therapy Selection of Cancer Liquid Biopsies.OncoTargets and therapy · 2021Review
- Neutrophil-to-mean platelet volume ratio as a new predictor for overall and cancer-specific survival in patients with localized clear cell renal cell carcinoma.Archives of medical science : AMS · 2020Article
- Mean Platelet Volume Has Prognostic Value in Chronic Lymphocytic Leukemia.Cancer management and research · 2020Article
- Prognostic Significance of Mean Platelet Volume on Local Advanced Non-Small Cell Lung Cancer Managed with Chemoradiotherapy.Scientific reports · 2019Article
- Prognostic value of mean platelet volume to plateletcrit ratio in patients with osteosarcoma.Cancer management and research · 2019Article
- Article
- Elevated platelet distribution width predicts poor prognosis in hepatocellular carcinoma.Cancer biomarkers : section A of Disease markers · 2019Article
- Tumor marker index based on preoperative SCC and CYFRA 21-1 is a significant prognostic factor for patients with resectable esophageal squamous cell carcinoma.Cancer biomarkers : section A of Disease markers · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEsophageal cancer (EC) is the sixth most common cause of death from cancer. Altered mean platelet volume (MPV) levels were found in patients with malignancies.
objectiveThe present study investigated whether MPV can predict the survival in EC patients. MEHTODS: The clinical data of 236 consecutive EC patients between January 2009 and December 2009 in our center were retrospectively analyzed. The overall survival rate was estimated using Kaplan-Meier method. Cox proportional hazards models were fitted to model the relationships between patient characteristics and prognosis.
resultsDecreased MPV was significantly correlated with tumor location and tumor differentiation (p< 0.001). Moreover, survival analysis revealed that the overall survival of patients with MPV ⩽ 7.4 fL was significantly shorter than that of those with MPV > 7.4 fL. Multivariate analysis identified MPV as an independent poor prognostic factor for overall survival.
conclusionsReduced MPV is associated with worse survival outcome in EC.
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