Evidence map›Paper›PMID 29809280›Full record

ArticleCA: a cancer journal for clinicians2018

Ovarian cancer statistics, 2018.

Lindsey A Torre, Britton Trabert, Carol E DeSantis, Kimberly D Miller, Goli Samimi, Carolyn D Runowicz, Mia M Gaudet, Ahmedin Jemal, Rebecca L Siegel

3 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in CA: a cancer journal for clinicians, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 2,080 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,080citing papers in PubMed, 5 pooled it
382.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05641506 phase2unknown statusnot on this mapstarted 2022, after this paper: background citation

An Open-label, Phase II Clinical Trial of of a Chinese Patent Medicine Yangzhengxiaoji Capsule to Improve the Adverse Reactions Nausea of Niraparib in in the First-line Maintenance Treatment in Advanced Epithelial Ovarian Cancer (EOC) Patients

TypeinterventionalSponsorSichuan Cancer Hospital and Research InstituteRan2022 to 2025Enrolled50ConditionsOvarian CancerArmsYangzheng Xiaoji, Niraparib
NCT06084195 narecruitingnot on this mapstarted 2023, after this paper: background citation

Unravelling Tumour Biology In Ovarian Cancer With Precision Imaging

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2023 to 2029Enrolled120ConditionsHigh Grade Serous Ovarian CancerArmsBlood sample and tissue sample
NCT06253559 completednot on this map

Clinical and Pathological Characteristics of Women With Ovarian Cancers, A National, Retrospective Cross-Sectional Study in Syria During the War

TypeobservationalSponsorLatakia UniversityRan2017 to 2023Enrolled531ConditionsOvarian Cancer
3 · Its place in the literature

Who cites it

2,080 citing papers in PubMed, 5 syntheses or guidelines pooled it, 3,678 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Causal inference in the diagnosis and prognosis of ovarian cancer: current state and future directions.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Pooled it
  6. Article
  7. A photothermal ablation strategy for orthotopic ovarian cancerInternational journal of pharmaceutics: X · 2026
    Article
  8. Article
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  13. Review
  14. Article
  15. Mechanistic Insights intoInternational journal of molecular sciences · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. The KPROCS Study: A Real-World and Research Resource to Investigate Multilevel Determinants of Ovarian Cancer Treatment and Survival.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  20. Article

2,020 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lindsey A TorreScientist, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.
Britton TrabertEarl Stadtman Investigator, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Carol E DeSantisPrincipal Scientist, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.ORCID 0000-0002-9382-6009
Kimberly D MillerSenior Associate Scientist, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.
Goli SamimiProgram Director, Breast and Gynecologic Cancer Research Group, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Carolyn D RunowiczExecutive Associate Dean for Academic Affairs and Professor, FL International University Herbert Wertheim College of Medicine, Miami, FL.
Mia M GaudetScientific Director, Behavioral and Epidemiologic Research Group, American Cancer Society, Atlanta, GA.
Ahmedin JemalScientific Vice President, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.
Rebecca L SiegelScientific Director, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.
American Cancer Society · USNational Institutes of Health · USFlorida International University · US

Funding

Hormone-Related CancersZIACP010126 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GIERACH, GRETCHEN · 2009 to 2025
$103.5M
Therapeutic and Diagnostic Factors as Related to Cancer RiskZIACP010128 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GIERACH, GRETCHEN · 2009 to 2025
$8.1M
Intramural NIH HHS ZIA CP010126
6 · The paper itself

Abstract

In 2018, there will be approximately 22,240 new cases of ovarian cancer diagnosed and 14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society provides an overview of ovarian cancer occurrence based on incidence data from nationwide population-based cancer registries and mortality data from the National Center for Health Statistics. The status of early detection strategies is also reviewed. In the United States, the overall ovarian cancer incidence rate declined from 1985 (16.6 per 100,000) to 2014 (11.8 per 100,000) by 29% and the mortality rate declined between 1976 (10.0 per 100,000) and 2015 (6.7 per 100,000) by 33%. Ovarian cancer encompasses a heterogenous group of malignancies that vary in etiology, molecular biology, and numerous other characteristics. Ninety percent of ovarian cancers are epithelial, the most common being serous carcinoma, for which incidence is highest in non-Hispanic whites (NHWs) (5.2 per 100,000) and lowest in non-Hispanic blacks (NHBs) and Asians/Pacific Islanders (APIs) (3.4 per 100,000). Notably, however, APIs have the highest incidence of endometrioid and clear cell carcinomas, which occur at younger ages and help explain comparable epithelial cancer incidence for APIs and NHWs younger than 55 years. Most serous carcinomas are diagnosed at stage III (51%) or IV (29%), for which the 5-year cause-specific survival for patients diagnosed during 2007 through 2013 was 42% and 26%, respectively. For all stages of epithelial cancer combined, 5-year survival is highest in APIs (57%) and lowest in NHBs (35%), who have the lowest survival for almost every stage of diagnosis across cancer subtypes. Moreover, survival has plateaued in NHBs for decades despite increasing in NHWs, from 40% for cases diagnosed during 1992 through 1994 to 47% during 2007 through 2013. Progress in reducing ovarian cancer incidence and mortality can be accelerated by reducing racial disparities and furthering knowledge of etiology and tumorigenesis to facilitate strategies for prevention and early detection. CA Cancer J Clin 2018;68:284-296. © 2018 American Cancer Society.

Indexed as

AdultAgedAged, 80 and overAmerican Cancer SocietyCarcinomaEarly Detection of CancerFemaleHealth Status DisparitiesHumansIncidenceMiddle AgedOvarian NeoplasmsPrognosisUnited Statesepidemiologyepithelial ovarian cancershealth disparitiesovarian neoplasms

Identifiers

PMID29809280
PMCPMC6621554
OpenAlexW2807649309

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.