Evidence map›Paper›PMID 29809266›Full record

ArticleJournal of pediatric ophthalmology and strabismus2018

Spontaneous Reattachment of the Medial Rectus After Free Tenotomy.

Daniel L Adams, Brittany C Rapone, John R Economides, Jonathan C Horton

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric ophthalmology and strabismus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Interocular Suppression in Primary Visual Cortex in Strabismus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Daniel L Adams
Brittany C Rapone
John R Economides
Jonathan C Horton
University of Trento · ITUniversity of California, San Francisco · US

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAMBA, DEEPAK ASHOK · 1985 to 2024
$16.8M
STRUCTURAL BASIS OF AMBLYOPIA AND STRABISMUSR01EY010217 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HORTON, JONATHAN C · 1993 to 2018
$8.5M
Horton_Admin_Supplement_EY029703R01EY029703 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HORTON, JONATHAN C · 2019 to 2024
$3.4M
Structural Basis of Amblyopia and StrabismusR56EY010217 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HORTON, JONATHAN C · 2008 to 2008
$369k
NEI NIH HHS P30 EY002162NEI NIH HHS R01 EY010217NEI NIH HHS R01 EY029703NEI NIH HHS R56 EY010217
6 · The paper itself

Abstract

purposeTo assess the outcome of free tenotomy of the medial rectus muscle in post-natal monkeys.

methodsThe medial rectus muscle was disinserted in both eyes of 6 macaques at age 4 weeks to induce an alternating exotropia. After the impact on the visual cortex and superior colliculus was investigated, the animals were examined post-mortem to assess the anatomy of the medial rectus muscles.

resultsAfter tenotomy, the monkeys eventually recovered partial adduction. Necropsy revealed that all 12 medial rectus muscles had reattached to the globe. They were firmly connected via an abnormally long tendon, but at the native insertion site.

conclusionsMedial rectus muscles are able to reattach spontaneously to the eye following free tenotomy in post-natal macaques. The early timing of surgery and the large size of the globe relative to the orbit may explain why reinsertion occurs more readily in monkeys than in children with a lost muscle after strabismus surgery. [J Pediatr Ophthalmol Strabismus. 2018;55(5):335-338.].

Indexed as

TenotomyAnimalsExotropiaMacaca mulattaMaleOculomotor MusclesOphthalmologic Surgical ProceduresSuperior ColliculiVisual Cortex

Identifiers

PMID29809266
PMCPMC6924507
OpenAlexW2806915287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.