Evidence map›Paper›PMID 29809148›Full record

ArticleeLife2018

Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.

Xun X Bao, Christos Spanos, Tomoko Kojidani, Eric M Lynch, Juri Rappsilber, Yasushi Hiraoka, Tokuko Haraguchi, Kenneth E Sawin

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Therapeutic targeting of exportin-1 beyond nuclear export.Trends in pharmacological sciences · 2025
    Review
  5. Review
  6. Nuclear transport proteins: structure, function, and disease relevance.Signal transduction and targeted therapy · 2023
    Review
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  8. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Xun X BaoWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0003-4733-3550
Christos SpanosWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0002-4376-8242
Tomoko KojidaniAdvanced ICT Research Institute Kobe, National Institute of Information and Communications Technology, Kobe, Japan.
Eric M LynchWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID https://orcid.org/0000-0001-5897-5167
Juri RappsilberWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0001-5999-1310
Yasushi HiraokaAdvanced ICT Research Institute Kobe, National Institute of Information and Communications Technology, Kobe, Japan.ORCID http://orcid.org/0000-0001-9407-8228
Tokuko HaraguchiAdvanced ICT Research Institute Kobe, National Institute of Information and Communications Technology, Kobe, Japan.ORCID http://orcid.org/0000-0002-3813-6785
Kenneth E SawinWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.ORCID http://orcid.org/0000-0002-2607-2219
Wellcome Centre for Cell Biology · GBNational Institute of Information and Communications Technology · JPJapan Women's University · JPUniversity of Washington · US

Funding

Wellcome Trust 091020Wellcome Trust 094517Wellcome Trust 103139/Z/13/ZWellcome Trust 108504Wellcome Trust 203149Wellcome Trust 91020Wellcome Trust 94517
6 · The paper itself

Abstract

Non-centrosomal microtubule organizing centers (MTOCs) are important for microtubule organization in many cell types. In fission yeast

Indexed as

Active Transport, Cell NucleusCarrier ProteinsCytoplasmExportin 1 ProteinKaryopherinsMicrotubule-Associated ProteinsMicrotubule-Organizing CenterMicrotubulesMolecular Docking SimulationNuclear EnvelopeNuclear PoreReceptors, Cytoplasmic and NuclearSchizosaccharomycesSchizosaccharomyces pombe ProteinsSpindle ApparatusCarrier ProteinsExportin 1 ProteinKaryopherinsMicrotubule-Associated ProteinsMto1 protein, S pombemto2p protein, S pombeReceptors, Cytoplasmic and NuclearSchizosaccharomyces pombe Proteinscell biologyexportinmicrotubulemicrotubule organizing centernuclear poreS. pombe

Identifiers

PMID29809148
PMCPMC6008054
OpenAlexW2951383255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.